DPP4 Inhibitor Screening Kit

Cat.No.: Kit-0315
Product Overview: This kit can be used for screening of DPP4 inhibitors. (100 assays)
Size: 100 assays
Description: Dipeptidyl peptidase-4 (DPP4) inhibitors have emerged as a new class of oral antidiabetic agents. These inhibitors promote glucose homeostasis by inhibiting degradation of glucosedependent insulinotropic polypeptide and glucagon-like peptide-1 by DPP4. Glucagon-like peptide-1 extends the action of insulin while suppressing the release of glucagon. In DPP4 Inhibitor Screening Kit, DPP4 cleaves a substrate to release a quenched fluorescent group (Em/Ex = 360/460 nm). In presence of a DPP4 inhibitor, the cleavage will be inhibited. The kit provides a rapid, simple, sensitive, and reliable test, as well as, suitable for high throughput screening of DPP4 inhibitors. Sitagliptin is included as a control inhibitor to compare the efficacy of the test inhibitors.
Usage: This product is furnished for LABORATORY RESEARCH USE ONLY. Not for diagnostic or therapeutic use.
Kit Components: DPP4 Assay BufferDPP4 SubstrateDPP4 EnzymeDPP4 Inhibitor (Sitagliptin)
Detection method: Fluorescence Plate ReaderFluorometer

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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