EZH2 (A677G) Chemiluminescent Assay Kit
Cat.No. : | Kit-1723 |
Product Overview : | EZH2 is the catalytic subunit of the PRC2/EED-EZH2 complex, which methylates Lys9 (H3K9me) and Lys27 (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate Lys27 of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1, CDKN2A and retinoic acid target genes. EZH2 can also methylate non-histone proteins such as the transcription factor GATA4. |
- Specification
- Gene Information
- Related Products
Size : | 96 reactions |
Storage : | One year from date of receipt when stored as directed. |
Products Types
◆ Recombinant Protein | ||
EZH2-879H | Recombinant Human EZH2 Protein, His (Fc)-Avi-tagged | +Inquiry |
EZH2-46H | Recombinant Human EZH2 Protein, His-tagged | +Inquiry |
EZH2-285H | Recombinant Human EZH2 Protein, GST-tagged | +Inquiry |
EZH2-1353R | Recombinant Rhesus Macaque EZH2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ezh2-991M | Recombinant Mouse Ezh2 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
EZH2-6487HCL | Recombinant Human EZH2 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1726 | EZH2 Chemiluminescent Assay Kit | +Inquiry |
Kit-1724 | EZH2 (Y641F) Chemiluminescent Assay Kit | +Inquiry |
Kit-1727 | EZH2 Homogeneous Assay Kit | +Inquiry |
Kit-1725 | EZH2 (Y641N) Chemiluminescent Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket