|Product Overview:||FBXL11, also known as KDM2A, JHDM1A, and Ndy2, is a histone lysine demethylase that exhibits demethylation activity toward histone H3 lysine 36.|
|Description:||The FBXL11 Homogeneous Assay Kit is designed to measure the activity of the FBXL11 for screening and profiling applications. The key to the FBXL11 Homogeneous Assay Kit is a highly specific antibody that recognizes demethylated substrate. With this kit, only three simple steps on a microtiter plate are required for demethylase activity detection. First, a sample containing FBXL11 enzyme is incubated with the biotinylated substrate. Next, acceptor beads and primary antibody are added, then donor beads, followed by reading the Alpha-counts.|
|Applications:||Great for studying enzyme kinetics and HTS applications.|
|Storage:||Stable for at least one year from date of receipt when stored as directed. Be sure to store each component at the proper storage temperature.|
|Kit Components:||FBXL11: 15 µg; -80°C Primary antibody 16-2: 10 µl; -80°C Biotinylated histone H3 peptide substrate: 500 rxns; -80°C 4x FBXL11 assay buffer 1: 2 ml; -20°C 4x FBXL11 assay buffer 2 (Incomplete Buffer): 1 ml; -20°C 4x Detection buffer: 2 ml; -20°C|
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