Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Active GMP Recombinant Human GDF11 Protein

Cat.No. : GDF11-137HG
Product Overview : Recombinant Human GDF11, Asn299-Ser407, was produced in E. coli using non-animal reagents in an animal-free facility under cGMP guidelines.
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Species : Human
Form : Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
Bio-activity : Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. Schwall, R.H. et al. (1991) Method Enzymol. 198:340.
Molecular Mass : Predicted Molecular Mass: 12.6 (monomer) kDa
SDS-PAGE: 12 kDa, reducing conditions
N-terminal Sequence Analysis : Met-Asn299-Leu-Gly-Leu-Asp-(Cys)-Asp-Glu-His
Endotoxin : <0.01 EU per 1 μg of the protein by the LAL method.
Purity : >95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Storage : Avoid repeated freeze-thaw cycles.
12 months, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : Reconstitute at 100 μg/mL in 4 mM HCl.
Quality Statement : Our GMP proteins are produced according to relevant sections of the following documents: WHO TRS, No. 822, 1992 Annex 1, Good Manufacturing Practices for Biological Products; USP Chapter 1043, Ancillary Materials for Cell, Gene and Tissue-Engineered Products and USP Chapter 92, Growth Factors and Cytokines Used in Cell Therapy Manufacturing.
Shipping : The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.
Gene Name : GDF11 growth differentiation factor 11 [ Homo sapiens ]
Official Symbol : GDF11
Synonyms : GDF11; growth differentiation factor 11; growth/differentiation factor 11; BMP 11; GDF-11; bone morphogenetic protein 11; BMP11; BMP-11;
Gene ID : 10220
mRNA Refseq : NM_005811
Protein Refseq : NP_005802
MIM : 603936
UniProt ID : O95390

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
Can GDF11 protein be used to treat some diseases with stem cell therapy? 12/25/2019

The protein can be used to treat some diseases through stem cell therapy, such as using the promoter of GDF11 to activate the self-renewal and regenerative ability of stem cells.

What diseases can GDF11 protein be used as a therapeutic target? 12/13/2019

GDF11 protein can be used as a therapeutic target for a variety of diseases such as muscular dystrophy, osteoporosis, cardiovascular diseases and neurodegenerative diseases.

What is the role of GDF11 protein on bone growth? 12/10/2019

GDF11 protein inhibits the differentiation of well-developed chondrocytes in bone growth plates into osteoblasts, thereby inhibiting bone growth.

Can GDF11 protein be intervened with drugs? 12/02/2019

The GDF11 protein can be intervened by means of drugs, such as using soluble GDF11 receptors to increase the activity of the GDF11 signaling pathway.

Does GDF11 protein promote muscle growth? 10/10/2019

In young animals, GDF11 promotes muscle growth, but in older adults and mice, its effect is not significant.

Does GDF11 protein drive neuroblast production and growth? 09/29/2019

This protein promotes the production and growth of neuroblasts and also plays an important role in the differentiation and function of neural stem cells.

Customer Reviews (3)

Write a review
Reviews
04/19/2022

    The repeatability of GDF11 is very good, which can ensure the reliability of the experimental results, and also facilitate the subsequent research and application.

    05/23/2020

      After using GDF11, my experimental results are more stable and reliable, and also convenient for subsequent data analysis.

      03/09/2020

        The band intensity of GDF11 in Western blot was high, which improved the signal-to-noise ratio of the experiment.

        Ask a Question for All GDF11 Products

        Required fields are marked with *

        My Review for All GDF11 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends