Pertactin (PRN) is a surface-located protein produced by Bordetella pertussis.
Due to its immunogenic and protective properties, pertactin protein is included in acellular pertussis vaccines. The contribution of this protein to Bordetella pathogenesis is under investigation, however, it appears to play a role in overcoming neutrophil-mediated clearance of Bordetella during early stages of establishing an infection. Pertactin is one of the most polymorphic B. pertussis proteins, occurring in the population in more than 13 variations.
Each vial, when reconstituted with 0.5 ml of sterile water, contains 50.0 ug of protein in 5 mM HEPES, 0.15 M NaCl, 1.25% Trehalose. Handle the product gently, do not vortex.
This product was supplied lyphilized powder, and sealed under vacum. Store at 2-8 centigrade prior to and reconstitution reconstitution.
Good laboratory technique should be employed in the safe handling of this product. Wear appropriate laboratory attire including a lab coat, gloves and safety glasses. Nitrile gloves are recommended when handling lyophilized material. This product is intended for research purposes by qualified personnel only. It is not intended for use in humans or as a diagnostic agent.