Active Native C. botulinum C3 Enzyme
Cat.No. : | C3-001C |
Product Overview : | This product was highly purified from the supernatant of the culture of Clostridium botulinum type C by cation exchange, hydroxyapatite and gel filtration columns. |
- Specification
- Gene Information
- Related Products
Description : | This toxin ADP–ribosylates Rho and Rac, which are low-molecular weight GTP-binding proteins of animal cells, and interrupts the downstream signal transduction pathways. |
Source : | C. botulinum |
Species : | C. botulinum |
Form : | 1.33 mg/ml in 5 mM sodium phosphate buffer (pH 6.0), 50% glycerol |
Bio-activity : | Stimulation of human keratinocytes in culture was observed at 50 ng/ml. No toxic effect was observed in two mice injected with 5 ug of C3 enzyme, showing little contamination of lethal neurotoxins from the botulinus culuture in this preparation. |
Molecular Mass : | 24kDa |
Purity : | More than 90 % purity by SDS-PAGE (CBB staining) |
Applications : | 1) For the studies on the Rho-dependent signaling pathways in animal cells in vivo and in vitro. 2) ADP-ribosylation of small GTP proteins, such as Rho and Rac proteins. |
Storage : | Ship at 4centigrade or -20centigrade and store at -20centigrade (-80centigrade for long-term storage). |
Warning : | It should be handled carefully. Avoid mouth pipetting. Wear protective gloves on handling the toxin. Avoid contact with open wounds. Wash thoroughly any area of the body that makes contact with the toxin. |
Gene Name : | Mono-ADP-ribosyltransferase C3 [Clostridium botulinum BKT015925] |
Official Symbol : | CBC4_RS13695 |
Synonyms : | CBC4_RS13695; mono-ADP-ribosyltransferase C3; C3; C3 enzyme |
Gene ID : | 29748288 |
Protein Refseq : | WP_013720927.1 |
UniProt ID : | P15879 |
Products Types
◆ Recombinant Protein | ||
C3-2505H | Recombinant Human C3 protein(961-1040 aa), C-His-tagged | +Inquiry |
C3-732M | Recombinant Mouse C3 Protein, MYC/DDK-tagged | +Inquiry |
C3-4324R | Recombinant Rabbit C3 Protein | +Inquiry |
C3-4325S | Recombinant Swine C3 Protein | +Inquiry |
C3-7632M | Recombinant Mouse C3 protein, His-tagged | +Inquiry |
◆ Native Protein | ||
C3-194H | Native Human Complement C3c | +Inquiry |
C3-365H | Active Native Human C3 Protein | +Inquiry |
C3-01R | Native Rabbit C3 Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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