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Home > Products > Toxin > Native C. tetani Tetanus toxin C fragment

Native C. tetani Tetanus toxin C fragment

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Cat.No.:
TTC-112C
Product Overview:
The C terminal binding portion of tetanus toxin is not toxic but is taken up by pre-synaptic nerve terminals and exhibits trans-synaptic retrograde transport in central neurons similar to that of tetanus toxin. It is used to map neuronal connections and to target proteins to neurons.
Description:
Tetanus toxin is a neurotoxin that comprises of a heavy and a light chain linked by disulfide bridges. This neurotoxin enters the cytoplasm and releases the light chain component that subsequently inhibits the release of neurotransmitters. Studies have reported that the fragment C of tetanus toxin retains most of the determinants that interact with thyroid membranes, gangliosides and neural membranes.
Source:
C. tetani
Species:
C. tetani
Molecular Mass:
47 kDa
Applications:
The C terminal binding portion of tetanus toxin is not toxic but is taken up by pre-synaptic nerve terminals and exhibits trans-synaptic retrograde transport in central neurons similar to that of tetanus toxin. It is used to map neuronal connections and to target proteins to neurons.
Reconstitution:
Each vial, when reconstituted with 50μl of sterile distilled water, contains 10μg of tetanus toxin C-fragment in 0.01 M sodium phosphate, pH 7.5. To aid recovery, 0.1% albumin may be added.
Synonyms:
TTC; Tetanus toxin C fragment; Tetanus toxin


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-097-1828
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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