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Native D. calyx Calyculin A

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Cat.No.:
CalA-255D
Product Overview:
Calyculin A is a spiro ketal compound that contains phosphate, oxazole, nitrile, and amide functionalities. It occurs naturally in the marine sponge Discodermia calyx as a lipophilic metabolite.
Description:
CalA has been found to be a very potent inhibitor of various phosphatases, including type 1 and type 2A protein phosphatase, the endogenous phosphatase of smooth muscle myosin B, and the partially purified catalytic subunit from myosin B. It has also been shown to induce tumors in CD-1 mouse skin.
Source:
D. calyx
Species:
D. calyx
Form:
The product is soluble in ethanol (1 mg/ml).
Molecular Mass:
1009
Purity:
≥90% (HPLC)
Stability:
Stock solutions of this product should be prepared at a minimum of 1 mg/ml. The stock solution should be divided into aliquots with as high a concentration as possible and with a volume larger than 10 µl to minimize exposure to oxygen. In addition, argon or nitrogen should be layered over the stock solution if possible. Aliquots can be stored at -20 centigrade for a few months.
Storage:
Store at -20 centigrade
Synonyms:
Calyculin A


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Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-048-3343
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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