|Product Overview:||Calyculin A is a spiro ketal compound that contains phosphate, oxazole, nitrile, and amide functionalities. It occurs naturally in the marine sponge Discodermia calyx as a lipophilic metabolite.|
|Description:||CalA has been found to be a very potent inhibitor of various phosphatases, including type 1 and type 2A protein phosphatase, the endogenous phosphatase of smooth muscle myosin B, and the partially purified catalytic subunit from myosin B. It has also been shown to induce tumors in CD-1 mouse skin.|
|Form:||The product is soluble in ethanol (1 mg/ml).|
|Stability:||Stock solutions of this product should be prepared at a minimum of 1 mg/ml. The stock solution should be divided into aliquots with as high a concentration as possible and with a volume larger than 10 µl to minimize exposure to oxygen. In addition, argon or nitrogen should be layered over the stock solution if possible. Aliquots can be stored at -20 centigrade for a few months.|
|Storage:||Store at -20 centigrade|
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