"MPO" Related Products


Native Human Myeloperoxidase protein

Cat.No.: MPO-1657H
Product Overview: Native Human Myeloperoxidase was purified from Human Neutrophil.
Description: This heme protein catalyzes oxidations by hydrogen peroxide, including MPO- chloride mediated killing of microbes and tumor cells, inactivation of hemotactic factors, crosslinking of proteins and inclination of proteins.
Source: Human Neutrophil
Species: Human
Form: Lyophilized from 50 mM Na acetate, pH 6.0 with 100 mM NaCl
Bio-activity: 180-220 units per mg protein after lyophilization. One unit is defined as the amount of enzyme that decomposes one umole of hydrogen peroxide per minute at 25 centigrade, pH 6.0. Reaction mixture contains 30mM sodium phosphate, pH 6.1, 30mM guaiacol, and 0.0012% (0.35mM) hydrogen peroxide.
Molecular Mass: 130,000-150,000
Purity: >=95% by SDS-PAGE
Notes: Prepared from whole blood shown to be non reactive for HBsAg, anti-HCV, anti- HBc, and negative for anti-HIV 1 & 2 by FDA approved tests.
Storage: Store at -20 centigrade
Gene Name: MPO myeloperoxidase [ Homo sapiens ]
Official Symbol: MPO
Synonyms: MPO; myeloperoxidase;
Gene ID: 4353
mRNA Refseq: NM_000250
Protein Refseq: NP_000241
MIM: 606989
UniProt ID: P05164
Chromosome Location: 17q21.3-q23
Pathway: C-MYB transcription factor network, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; IL23-mediated signaling events, organism-specific biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; Selenium Pathway, organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem;
Function: chromatin binding; heme binding; heparin binding; metal ion binding; oxidoreductase activity; peroxidase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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