Active Native Porcine CAPN2 protein
Cat.No. : | CAPN2-22P |
Product Overview : | Native Porcine CAPN2 purified from porcine kidney. |
- Specification
- Gene Information
- Related Products
Description : | The two major isoforms, calpain I (-form) and calpain II (m-form), differ in their calcium requirement for activation. Calpain I requires only micromolar amounts of calcium (EC = 2 M), while calpain II requires millimolar amounts (EC = 1 mM). Calpains are heterodimers of 80 kDa and 30 kDa subunits. The 80 kDa unit has the catalytic site and is unique to each isozyme. The 30 kDa unit is a regulatory subunit and common to both calpain I and calpain II. The 80 kDa unit consists of four domains (I-IV). The 30 kDa unit has two domains (V and VI). Domain I is partially removed during autolysis. Domain II is the protease domain. Domain III exhibits a homology with typical calmodulin binding proteins and interacts with calcium binding domains (IV and VI) and frees domain II for protease activity. Domain IV is a calcium binding domain. Domain V contains a hydrophobic region and is essential for calpain interaction with membranes. Domain VI is a calcium binding domain. |
Source : | Porcine kidney |
Species : | Porcine |
Form : | Liquid |
Bio-activity : | 1000 units/mg |
Molecular Mass : | 109000 |
Stability : | Avoid freeze/thaw. Following initial thaw, aliquot and freeze (-70 centigrade). The enzyme will lose activity upon storage at 4 centigrade. |
Storage : | Store at -80 centigrade. |
Products Types
◆ Recombinant Protein | ||
CAPN2-785R | Recombinant Rat CAPN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CAPN2-122H | Recombinant Human CAPN2 protein, His-tagged | +Inquiry |
CAPN2-106C | Recombinant Cynomolgus Monkey CAPN2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CAPN2-587H | Recombinant Human CAPN2 Protein, His-tagged | +Inquiry |
Capn2-759M | Recombinant Mouse Capn2 Protein, MYC/DDK-tagged | +Inquiry |
◆ Native Protein | ||
CAPN2-350B | Native Bovine CAPN2 | +Inquiry |
◆ Lysates | ||
CAPN2-7863HCL | Recombinant Human CAPN2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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