Enterotoxin Type B Toxoid-222
Enterotoxin Type B Toxoid was produced in a native Staphylococcus aureus.
Staphylococcus aureus is a common commensal of the skin and mucosal membranes which causes significant illness worldwide through production of numerous Staphylococcal toxins. Food poisoning can result from consumption of foods containing preformed enterotoxins, SEA, SEB, SEC, SED and SEE resulting from Staphylococcal organisms. Other illnesses caused by this organism include toxic shock syndrome, scalded skin syndrome, pneumonia, and infective endocarditis. Staphylococcal toxins that act on cell membranes include alpha toxin, beta toxin, delta toxin, and Panton-Valentine leukocidin.
Each vial, when reconstituted with 500 ul water, the protein in 0.1 M Histidine, 0.1 M sodium Chloride Ph 7.0 with 5% Trehalose. Handle the product gently; do not vortex.
The endotoxin content, determined using a kinetic chromagenic LAL assay, is 2 EU/mg.
Care must be taken in the design of experiments with the toxoid because although toxicity has been reduced, sufficient toxicity may remain to cause death under certain conditions.
This product is provided as lyophilized powder, sealed under vacuum. Store at 2 - 8 centigrade prior to reconstitution. Following reconstitution, aliquot and freeze.
Good laboratory technique should be employed in the safe handling of this product. Wear appropriate laboratory attire including a lab coat, gloves and safety glasses. Nitrile gloves are recommended when handling lyophilized material. This product is intended for research purposes by qualified personnel only. It is not intended for use in humans or as a diagnostic agent.