Simple & convenient protocol.Can detect Plasmin activity as low as 10 ng in a variety of samples.Kit contains all necessary reagents for measuring plasmin activity.
Plasmin (EC 126.96.36.199) is a serine protease occurring in plasma as plasminogen. Upon activation via cleavage by plasminogen activators; plasmin solubilizes fibrin clots and activates and/or degrades compounds of the coagulation and complement systems. Plasminogen-Plasmin system has also been implicated in a wide variety of physiologic and pathologic processes, including tumor growth, invasion and metastasis. BioVision"s Plasmin activity assay kit utilizes the ability of Plasmin to proteolytically cleave a synthetic substrate and release a fluorophore, AMC, which can be easily quantified by fluorescence microplate readers. This assay kit is simple, rapid and can detect Plasmin activity as low as 10 ng in a variety of samples.
Detect the activity of Plasmin in plasma
For Research Use Only! Not For Use in Humans
• Plasmin Assay Buffer• Plasmin Dilution Buffer• Plasmin Enzyme Standard (1 mg/ml)• Plasmin Substrate
Fluorescence (Ex/Em = 360/450 nm)