Simple & convenient protocol.
Can detect Plasmin activity as low as 10 ng in a variety of samples.
Kit contains all necessary reagents for measuring plasmin activity.
Plasmin (EC 220.127.116.11) is a serine protease occurring in plasma as plasminogen. Upon activation via cleavage by plasminogen activators; plasmin solubilizes fibrin clots and activates and/or degrades compounds of the coagulation and complement systems. Plasminogen-Plasmin system has also been implicated in a wide variety of physiologic and pathologic processes, including tumor growth, invasion and metastasis. Plasmin activity assay kit utilizes the ability of Plasmin to proteolytically cleave a synthetic substrate and release a fluorophore, AMC, which can be easily quantified by fluorescence microplate readers. This assay kit is simple, rapid and can detect Plasmin activity as low as 10 ng in a variety of samples.
Detect the activity of Plasmin in plasma
For Research Use Only! Not For Use in Humans
• Plasmin Assay Buffer
• Plasmin Dilution Buffer
• Plasmin Enzyme Standard (1 mg/ml)
• Plasmin Substrate
Fluorescence (Ex/Em = 360/450 nm)