Active Recombinant Cynomolgus DPP4 protein, His-tagged
Cat.No. : | DPP4-1203C |
Product Overview : | Recombinant Cynomolgus DPP4 protein(Asn 29 - Pro 766), fused with His tag, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Source : | HEK293 |
Species : | Cynomolgus |
Tag : | His |
Form : | Lyophilized from 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl, pH8.0. Normally trehalose is added as protectant before lyophilization. |
Bio-activity : | Measured by its ability to cleave the fluorogenic peptide substrate, Gly-Pro-7-amido-4-methylcoumarin (GP-AMC). The specific activity is >3500 pmol/min/μg(QC tested). |
Molecular Mass : | This protein carries a polyhistidine tag at the C-terminus.The protein has a calculated MW of 86.9 kDa. The protein migrates as 100-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Proteinlength : | Asn29-Pro766 |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE.>90% as determined by SEC-MALS. |
Storage : | For long term, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Products Types
◆ Recombinant Protein | ||
DPP4-203H | Recombinant Human DPP4 Protein, Fc-tagged | +Inquiry |
DPP4-2845H | Recombinant Human DPP4 Protein, GST-tagged | +Inquiry |
DPP4-040H | Recombinant Human DPP4 Protein, His-tagged | +Inquiry |
DPP4-783H | Recombinant Human DPP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
DPP4-792H | Recombinant Human DPP4 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
DPP4-31H | Active Native Human DPP4 | +Inquiry |
DPP4-197H | Native Human Dipeptidyl Peptidase IV | +Inquiry |
◆ Lysates | ||
DPP4-2979HCL | Recombinant Human DPP4 cell lysate | +Inquiry |
DPP4-733CCL | Recombinant Cynomolgus DPP4 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0317 | DPPIV/CD26 Assay Kit | +Inquiry |
Kit-0312 | Dipeptidyl peptidase IV Inhibitor Screening Assay Kit | +Inquiry |
Kit-0313 | DPP IV Immunocapture Activity Assay Kit | +Inquiry |
Kit-0315 | DPP4 Inhibitor Screening Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionDPP4 plays a crucial role in glucose homeostasis by cleaving incretin hormones. In diabetes, inhibiting DPP4 can enhance the action of these hormones, promoting insulin release and lowering blood sugar levels.
Common side effects of DPP4 inhibitors include respiratory and urinary tract infections, headache, and nasopharyngitis. However, they are generally well-tolerated.
Inhibitors of DPP4 are used in the treatment of type 2 diabetes to improve glycemic control. They work by prolonging the activity of incretin hormones, such as GLP-1, which stimulate insulin secretion.
DPP4 inhibitors are often used as monotherapy or in combination with other antidiabetic medications to achieve optimal glycemic control.
DPP4 inhibitors work by enhancing the effects of incretin hormones, while other diabetes medications may act on insulin sensitivity, insulin release, or glucose absorption.
Customer Reviews (3)
Write a reviewIts purity and efficacy make it an ideal choice for precise and accurate analysis, allowing me to generate reliable results.
By incorporating the DPP4 Protein into their studies, scientists can confidently conduct their research, ushering in groundbreaking discoveries and novel insights within their respective domains.
Its exceptional purity and functionality make it an ideal choice for accurate and precise analysis, ensuring reliable and reproducible results.
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