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Recombinant Cynomolgus FGFR3 Protein, His-tagged

Cat.No. : FGFR3-1224C
Product Overview : Recombinant cynomolgus FGFR3 (XP_005554344.1) (Met1-Gly375) was expressed with a polyhistidine tag at the C-terminus. Cynomolgus and Rhesus FGFR3 sequences are identical.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Cynomolgus
Tag : His
Predicted N Terminal : Glu 23
Form : Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
Molecular Mass : The recombinant cynomolgus FGFR3 consists 364 amino acids and predicts a molecular mass of 39.5 kDa.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >95 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : FGFR3 fibroblast growth factor receptor 3 [ Macaca fascicularis ]
Official Symbol : FGFR3
Synonyms : fibroblast growth factor receptor 3
Gene ID : 102128947
mRNA Refseq :
Protein Refseq :
MIM :
UniProt ID :
Chromosome Location : chromosome: 5
Pathway : Bladder cancer, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MicroRNAs in cancer, organism-specific biosystem

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does FGFR3 testing assist in personalized medicine approaches? 12/13/2022

FGFR3 testing helps identify specific genetic mutations, allowing for personalized treatment plans tailored to an individual's genetic profile.

Is FGFR3 testing routinely conducted in cancer diagnosis? 06/25/2022

FGFR3 testing is becoming more common, especially in cases where specific cancers associated with FGFR3 mutations are suspected.

Can FGFR3 be a prognostic marker in cancer? 12/01/2016

Yes, FGFR3 status can serve as a prognostic marker, influencing the prediction of disease progression and patient outcomes.

Are there targeted therapies based on FGFR3 in cancer treatment? 07/23/2016

Yes, FGFR3-targeted therapies are being developed for cancer treatment, particularly for patients with FGFR3 mutations.

How is FGFR3 targeted in cancer therapy? 03/13/2016

FGFR3-targeted therapies may involve small molecule inhibitors or monoclonal antibodies that specifically block the activity of mutated FGFR3.

Customer Reviews (3)

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Reviews
01/13/2020

    Researchers who have utilized FGFR3 protein praise its exceptional performance and reliability in their experiments.

    03/26/2018

      Its high sensitivity enables the identification of low abundance targets, making it highly valuable in immunological research.

      08/29/2017

        Its stability and compatibility with electron microscopy techniques make it an ideal candidate for studying protein structures at high resolution.

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