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Active Recombinant Cynomolgus IFNG Protein

Cat.No. : IFNG-1165C
Product Overview : Recombinant cynomolgus IFNG [Identical to rhesus IFNG (NP_001028077.1)] (Gln24-Gln165) was expressed and purified with an initial Met.
  • Specification
  • Gene Information
  • Related Products
Source : E. coli
Species : Cynomolgus
Predicted N Terminal : Met
Form : Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
Bio-activity : Measured by its binding ability in a functional ELISA.Immobilized Cynomolgus IFNG at 10 μg/ml (100 μl/well) can bind Cynomolgus IFNGR1-Fc. The EC50 of Cynomolgus IFNGR1-Fc is 20.28-47.32 ng/ml.
Molecular Mass : The recombinant cynomolgus IFNG consists of 143 amino acids and has a calculated molecular mass of 16.9 kDa. It migrates as an 17 kDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >90 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : IFNG interferon, gamma [ Macaca fascicularis ]
Official Symbol : IFNG
Synonyms : IFN-gamma; interferon-gamma
Gene ID : 102128291
mRNA Refseq : NM_001287657
Protein Refseq : NP_001274586
MIM :
UniProt ID : P63309
Chromosome Location : chromosome: 11
Pathway : African trypanosomiasis, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the role of IFNG in tumor immunotherapy? 09/23/2022

IFNG plays an important role in tumor immunotherapy, which can activate the immune response of tumor cells, promote apoptosis of tumor cells and inhibit the proliferation of tumor cells.

What is the current progress in drug development for IFNG? 12/19/2021

The development of drugs for IFNG is currently in clinical trials, including monoclonal antibodies against IFNG receptors and inhibitors against IFNG signaling pathways.

How is IFNG related to muscle wasting? 12/02/2021

Studies have shown that IFNG can inhibit the occurrence of muscle atrophy, but the specific mechanism is not clear.

How can IFNG be used as a biomarker in clinical practice? 03/01/2021

In clinical practice, the expression level of IFNG can be measured to predict the progression and prognosis of the disease, and to guide the choice of treatment regimen.

Are there other coding variants in the IFNG gene? 07/12/2020

Yes, there are other coding variants in the IFNG gene that may have different functions and expression patterns.

Is the expression of IFNG affected by environmental factors? 05/26/2020

Such as nutritional status, inflammation levels, etc. Yes, the expression of IFNG is affected by environmental factors, such as nutritional status, inflammation level, etc.

Customer Reviews (3)

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Reviews
12/17/2022

    It is analyzed by X-ray crystallography or other crystallization techniques and has good crystallization properties.

    06/10/2022

      Easy to attach to the surface of cells or materials.

      04/02/2022

        IFNG products have a complete range of specifications for experimental designs of different sizes and needs.

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