Recombinant Human ACACA protein, His/MBP-tagged
Cat.No. : | ACACA-376H |
Product Overview : | Recombinant Human ACACA(307-430 aa) fused with His/MBP tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. |
Source : | E. coli |
Species : | Human |
Tag : | His/MBP |
Form : | Liquid in PBS |
Protein length : | 307-430 aa |
Purity : | SDS-PAGE >90% |
Applications : | WB Positive Control |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | ACACA acetyl-CoA carboxylase alpha [ Homo sapiens ] |
Official Symbol : | ACACA |
Synonyms : | ACACA; acetyl-CoA carboxylase alpha; ACAC, ACC, acetyl Coenzyme A carboxylase alpha; acetyl-CoA carboxylase 1; ACC1; acetyl CoA carboxylase 1; ACC-alpha; acetyl-Coenzyme A carboxylase alpha; ACC; ACAC; ACCA; ACACAD; |
Gene ID : | 31 |
mRNA Refseq : | NM_198834 |
Protein Refseq : | NP_942131 |
MIM : | 200350 |
UniProt ID : | Q13085 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionAcetyl-CoA carboxylase alpha protein performs its function through the transfer of a carboxyl group from bicarbonate to acetyl-CoA.
Acetyl-CoA carboxylase alpha protein plays important roles in energy metabolism, fatty acid synthesis, and insulin signaling.
The expression of acetyl-CoA carboxylase alpha protein is regulated by transcriptional and post-transcriptional mechanisms.
Acetyl-CoA carboxylase alpha protein is closely involved in the regulation of lipid metabolism.
Acetyl-CoA carboxylase alpha protein interacts with various cellular components, including cytoskeletal proteins and membrane lipids.
Acetyl-CoA carboxylase alpha protein is implicated in various human diseases, such as obesity, diabetes, and cancer.
The primary function of acetyl-CoA carboxylase alpha protein is to catalyze the conversion of acetyl-CoA to malonyl-CoA.
Modulating the activity of acetyl-CoA carboxylase alpha protein is a potential therapeutic strategy for metabolic disorders and cancer.
Acetyl-CoA carboxylase alpha protein is a multi-subunit enzyme with a biotin carboxylase domain and a carboxyltransferase domain.
The regulation of acetyl-CoA carboxylase alpha protein involves multiple cellular pathways, including AMPK and mTOR signaling.
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