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Recombinant Human ACVR1B protein, GST/His-tagged

Cat.No. : ACVR1B-231H
Product Overview : Recombinant Human ACVR1B, transcript variant 1, fused with GST tag at N-terminal and His tag at C-terminal was expressed in E. coli.
  • Specification
  • Gene Information
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Description : This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.
Source : E. coli
Species : Human
Tag : GST/His
Form : 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
Molecular Mass : 84.8 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ACVR1B activin A receptor, type IB [ Homo sapiens ]
Official Symbol : ACVR1B
Synonyms : ACVR1B; activin A receptor, type IB; ACVRLK4; activin receptor type-1B; ActRIB; ALK4; SKR2; activin receptor-like kinase 4; activin A receptor, type II-like kinase 4; serine/threonine-protein kinase receptor R2; ACTRIB;
Gene ID : 91
mRNA Refseq : NM_004302
Protein Refseq : NP_004293
MIM : 601300
UniProt ID : P36896

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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