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Recombinant Human ACVRL1 Protein, His-tagged

Cat.No. : ACVRL1-360H
Product Overview : Recombinant human ACVRL1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
  • Specification
  • Gene Information
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Description : ACVRL1, also known as serine/threonine-protein kinase receptor R3, is a membrane-anchored proteoglycan whose core protein binds TGFf3 and has a short cytoplasmic domain with no discernible signaling structure. Also, this protein shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases.
Source : Insect cell
Species : Human
Tag : His
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass : 11.5kDa (103aa)18-28KDa (SDS-PAGE under reducing conditions.)
AA Sequence : DPVKPSRGPL VTCTCESPHC KGPTCRGAWC TVVLVREEGR HPQEHRGCGN LHRELCRGRP TEFVNHYCCD SHLCNHNVSL VLEATQPPSE QPGTDGQHHH HHH
Endotoxin : < 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity : >95% by SDS - PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.25mg/ml (determined by Absorbance at 280nm)
Gene Name : ACVRL1 activin A receptor type II-like 1 [ Homo sapiens ]
Official Symbol : ACVRL1
Synonyms : ACVRL1; activin A receptor type II-like 1; ACVRLK1, ORW2; serine/threonine-protein kinase receptor R3; ALK1; HHT; HHT2; activin receptor-like kinase 1; TGF-B superfamily receptor type I; activin A receptor, type II-like kinase 1; ORW2; SKR3; ALK-1; TSR-I; ACVRLK1;
Gene ID : 94
mRNA Refseq : NM_000020
Protein Refseq : NP_000011
MIM : 601284
UniProt ID : P37023
Chromosome Location : 12q11-q14
Pathway : ALK1 pathway, organism-specific biosystem; ALK1 signaling events, organism-specific biosystem; Id Signaling Pathway, organism-specific biosystem; TGF-beta Receptor Signaling Pathway, organism-specific biosystem;
Function : ATP binding; SMAD binding; activin binding; activin receptor activity, type I; contributes_to activin receptor activity, type I; metal ion binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; receptor activity; receptor signaling protein serine/threonine kinase activity; transforming growth factor beta binding; contributes_to transforming growth factor beta receptor activity, type I; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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