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Recombinant Human ADAM15 Protein, GST-tagged

Cat.No. : ADAM15-277H
Product Overview : Human ADAM15 partial ORF ( AAH14566, 301 a.a. - 410 a.a.) recombinant protein with GST-tag at N-terminal.
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  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 37.73 kDa
AA Sequence : AQLVTGTSFSGPTVGMAIQNSICSP DFSGGVNMDHSTSILGVASSIAHEL GHSLGLDHDLPGNSCPCPGPAPAKT CIMEASTDFLPGLNFSNCSRRALEK ALLDGMGSCL
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ADAM15 ADAM metallopeptidase domain 15 [ Homo sapiens ]
Official Symbol : ADAM15
Synonyms : ADAM15; ADAM metallopeptidase domain 15; a disintegrin and metalloproteinase domain 15 (metargidin); disintegrin and metalloproteinase domain-containing protein 15; MDC15; metargidin; MDC-15; ADAM 15; metalloprotease RGD disintegrin protein; metalloproteinase-like, disintegrin-like, and cysteine-rich protein 15;
Gene ID : 8751
mRNA Refseq : NM_003815
Protein Refseq : NP_003806
MIM : 605548
UniProt ID : Q13444

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (4)

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In addition to breast cancer research, what other diseases is ADAM15 currently used to study? 04/05/2022

ADAM15 used in studies of liver and bladder cancers.

I want to buy ADAM15-related proteins, do you provide other proteins? 10/09/2021

We offer MMP9 and MMP2 proteins in addition to ADAM15 proteins.

Does ADAM15 affect H460 expression? 06/26/2020

ADAM15 affects the proliferation of H460 cells by regulating PI3K-AKT and MAPK-ERK signaling pathways.

Does adding GST tag have any effect on protein? 12/13/2019

Addition of GST tags can accelerate the solubilization of certain insoluble proteins.

Customer Reviews (2)

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Reviews
09/04/2021

    The purchased protein is suitable for WB experiments and I am satisfied with the results.

    05/17/2020

      The technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.

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