Recombinant Human ADH1B Protein, GST-tagged

• Cat.No.: ADH1B-345H
• Product Overview: Human ADH1B full-length ORF ( AAH33009.1, 1 a.a. - 375 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 66.99 kDa
• AA Sequence: MSTAGKVIKCKAAVLWEVKKPFSIE DVEVAPPKAYEVRIKMVAVGICRTD DHVVSGNLVTPLPVILGHEAAGIVE SVGEGVTTVKPGDKVIPLFTPQCGK CRVCKNPESNYCLKNDLGNPRGTLQ DGTRRFTCRGKPIHHFLGTSTFSQY TVVDENAVAKIDAASPLEKVCLIGC GFSTGYGSAVNVAKVTPGSTCAVFG LGGVGLSAVMGCKAAGAARIIAVDI NKDKFAKAKELGATECINPQDYKKP IQEVLKEMTDGGVDFSFEVIGRLDT MMASLLCCHEACGTSVIVGVPPASQ NLSINPMLLLTGRTWKGAVYGGFKS KEGIPKLVADFMAKKFSLDALITHV LPFEKINEGFDLLHSGKSIRTVLTF
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide [ Homo sapiens ]
• Official Symbol: ADH1B
• Synonyms: ADH1B; alcohol dehydrogenase 1B (class I), beta polypeptide; ADH2; alcohol dehydrogenase 1B; ADH, beta subunit; aldehyde reductase; alcohol dehydrogenase subunit beta; alcohol dehydrogenase 2 (class I), beta polypeptide
• Gene ID: 125
• mRNA Refseq: NM_000668
• Protein Refseq: NP_000659
• MIM: 103720
• UniProt ID: P00325