| Description : |
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008] |
| Source : |
Wheat Germ |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
49 kDa |
| AA Sequence : |
MGSLQPDAGNASWNGTEAPGGGARA TPYSLQVTLTLVCLAGLLMLLTVFG NVLVIIAVFTSRALKAPQNLFLVSL ASADILVATLVIPFSLANEVMGYWY FGKAWCEIYLALDVLFCTSSIVHLC AISLDRYWSITQAIEYNLKRTPRRI KAIIITVWVISAVISFPPLISIEKK GGGGGPQPAEPRCEINDQKWYVISS CIGSFFAPCLIMILVYVRIYQIAKR RTRVPPSRRGPDAVAAPPGGTERRP NGLGPERSAGPGGAEAEPLPTQLNG APGEPAPAGPRDTDALDLEESSSSD HAERPPGPRRPERGPRGKGKARASQ VKPGDSLPRRGPGATGIGTPAAGPG EERVGAAKASRWRGRQNREKRFTFV LAVVIGVFVVCWFPFFFTYTLTAVG CSVPRTLFKFFFWFGYCNSSLNPVI YTIFNHDFRRAFKKILCRGDRKRIV |
| Applications : |
Antibody Production
Functional Study
Compound Screening |
| Usage : |
Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
25 mM Tris-HCl of pH 8.0 containing 2% glycerol. |
