Recombinant Human AKT1 protein, Flag-tagged, Biotinylated

• Cat.No.: AKT1-30H
• Product Overview: Recombinant Human AKT1, catalytic domain [104-480(end) amino acids of accession number NP_005154.1] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.

Specification

• Source: Insect cell
• Species: Human
• Tag: Flag
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: 47 kDa
• Purity: >87% as determined by SDS-PAGE and CBB staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: AKT1 v-akt murine thymoma viral oncogene homolog 1 [ Homo sapiens ]
• Official Symbol: AKT1
• Synonyms: AKT1; AKT; PKB; PRKBA; RAC; PKB alpha; RAC-PK-alpha
• Gene ID: 207
• mRNA Refseq: NM_001014431
• Protein Refseq: NP_001014431
• MIM: 164730
• UniProt ID: P31749
• Chromosome Location: 14q32.32-q32.33
• Pathway: AKT phosphorylates targets in the cytosol, organism-specific biosystem; AKT phosphorylates targets in the nucleus, organism-specific biosystem; AKT-mediated inactivation of FOXO1A, organism-specific biosystem; Activation of BAD and translocation to mitochondria, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem
• Function: ATP binding; ATP binding; enzyme binding; identical protein binding; kinase activity; nitric-oxide synthase regulator activity; nucleotide binding; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine kinase activity