Recombinant Human ALPP protein, T7/His-tagged

• Cat.No.: ALPP-221H
• Product Overview: Recombinant human ALPP cDNA (23-506aa, derived from BC009647) fused with T7-His-TEV cleavage site Tag at N-terminal was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: T7/His
• Form: 1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, Sucrose and DTT.
• AA Sequence: MASMTGGQQMGRGHHHHHHGNLYFQ GGEFIIPVEEENPDFWNREAAEALG AAKKLQPAQTAAKNLIIFLGDGMGV STVTAARILKGQKKDKLGPEIPLAM DRFPYVALSKTYNVDKHVPDSGATA TAYLCGVKGNFQTIGLSAAARFNQC NTTRGNEVISVMNRAKKAGKSVGVV TTTRVQHASPAGTYAHTVNRNWYSD ADVPASARQEGCQDIATQLISNMDI DVILGGGRKYMFRMGTPDPEYPDDY SQGGTRLDGKNLVQEWLAKRQGARY VWNRTELMQASLDPSVTHLMGLFEP GDMKYEIHRDSTLDPSLMEMTEAAL RLLSRNPRGFFLFVEGGRIDHGHHE SRAYRALTETIMFDDAIERAGQLTS EEDTLSLVTADHSHVFSFGGYPLRG SSIFGLAPGKARDRKAYTVLLYGNG PGYVLKDGARPDVTESESGSPEYRQ QSAVPLDEETHAGEDVAVFARGPQA HLVHGVQEQTFIAHVMAFAACLEPY TACDLAPPAGTTD
• Purity: >90% by SDS-PAGE
• Applications: 1. May be used for in vitro ALPP mediated Insulin-like growth factor (IGF) pathway regulation study in stem cell proliferation by coating this protein as matrix protein or use it as soluble factor.2. May be used for protein-protein interaction mapping.3. As enzymatic substrate for various proteases.4. Potential biomarker protein for tumor diagnosis, such as ovarian cancer, et al.5. As immunogen for specific antibody production.
• Storage: Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 7 days.

Gene Information

• Gene Name: ALPP alkaline phosphatase, placental [ Homo sapiens ]
• Official Symbol: ALPP
• Synonyms: ALPP; alkaline phosphatase, placental; alkaline phosphatase, placental (Regan isozyme); alkaline phosphatase, placental type; Regan isozyme; PLAP-1; glycerophosphatase; alkaline phosphomonoesterase; placental alkaline phosphatase 1; alkaline phosphatase Regan isozyme; ALP; PALP; PLAP; FLJ61142
• Gene ID: 250
• mRNA Refseq: NM_001632
• Protein Refseq: NP_001623
• MIM: 171800
• UniProt ID: P05187
• Chromosome Location: 2q37.1
• Pathway: Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem
• Function: alkaline phosphatase activity; alkaline phosphatase activity; hydrolase activity; metal ion binding