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Recombinant Human AMH protein, His-tagged

Cat.No. : AMH-892H
Product Overview : Recombinant Human AMH (NP_000470.2) (Leu25-Arg560) fused with His tag was produced in HEK293 cells.
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Source : HEK293
Species : Human
Tag : His
Form : Lyophilized from sterile 20 mM Tris, 150 mM NaCl, pH 8.0.
Molecular Mass : The recombinant human AMH consists of 555 amino acids and predicts a molecular mass of 59.1 kDa. As a result of proteolytic cleavage, it migrates as three bands (63.6, 40.5, 35 kDa) corresponding to the full length and the cleaved two polypeptides respectively in SDS-PAGE under reducing conditions.
Protein Length : Leu25-Arg560
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 90 % as determined by SDS-PAGE.
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : AMH anti-Mullerian hormone [ Homo sapiens ]
Official Symbol : AMH
Synonyms : AMH; anti-Mullerian hormone; muellerian-inhibiting factor; MIS; anti-Muellerian hormone; Mullerian inhibiting factor; Mullerian inhibiting substance; muellerian-inhibiting substance; MIF;
Gene ID : 268
mRNA Refseq : NM_000479
Protein Refseq : NP_000470
MIM : 600957
UniProt ID : P03971

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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How does AMH interact with other hormones, such as follicle-stimulating hormone (FSH) or estrogen, in coordinating reproductive functions? 01/10/2021

AMH interacts with hormones like FSH and estrogen to modulate the balance between follicular development and follicle selection.

What are the genetic and epigenetic factors that influence AMH expression and its variations among individuals? 03/22/2020

AMH expression is influenced by genetic variations and epigenetic modifications that can contribute to inter-individual differences in AMH levels.

How does AMH influence the differentiation of Sertoli cells and the development of the male reproductive system? 04/16/2019

AMH inhibits the development of M眉llerian ducts in males, promoting the differentiation of Sertoli cells and the formation of the male reproductive system.

What are the functional consequences of AMH deficiency or overexpression on fertility and reproductive health? 02/19/2019

Deficiency or overexpression of AMH can lead to reproductive abnormalities, such as altered fertility, impaired gonadal development, or disorders of sexual differentiation.

What is the role of AMH in the regulation of female reproductive organ development and folliculogenesis? 11/20/2018

In females, AMH plays a role in regulating the regression of M眉llerian ducts and inhibiting follicular development.

Can modulating AMH signaling be a potential therapeutic strategy for infertility or reproductive disorders? 06/20/2018

Modulating AMH signaling pathways may hold therapeutic potential for infertility treatments and the management of reproductive disorders by manipulating follicular development or regulating reproductive organ development.

How does AMH contribute to the pathogenesis of reproductive disorders, such as polycystic ovary syndrome (PCOS) or disorders of sexual development (DSD)? 05/03/2018

Dysregulation of AMH has been associated with reproductive disorders, including polycystic ovary syndrome (PCOS) characterized by increased AMH levels, and disorders of sexual development (DSD) associated with AMH deficiency or insensitivity.

Can AMH serve as a biomarker for assessing ovarian reserve or predicting ovarian response to fertility treatments? 12/28/2017

AMH levels can serve as a valuable biomarker for assessing ovarian reserve and predicting ovarian response to fertility treatments like in vitro fertilization (IVF).

How is AMH expression regulated during gonadal development and sex determination? 09/12/2017

AMH expression is tightly regulated during gonadal development and sex determination, primarily controlled by the transcription factors involved in testis development, such as SRY (Sex-determining Region Y) protein.

What are the downstream signaling pathways activated by AMH and their roles in reproductive organ development? 01/03/2017

AMH activates the transforming growth factor-beta (TGF-尾) signaling pathway, which plays a crucial role in regulating reproductive organ development and functions.

Customer Reviews (3)

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Reviews
12/18/2021

    Reduced assay optimization time for faster results.

    02/02/2019

      High-throughput compatibility for efficient data acquisition.

      02/12/2018

        Stable reagents for long-term assay reproducibility.

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