Recombinant Human ASCL1 protein, His-tagged

• Cat.No.: ASCL1-22H
• Product Overview: Recombinant Human ASCL1, fused with N-His, was expressed in E. coli.

Specification

• Description: Transcriptional regulator. May play a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Involved in the initiation of neuronal differentiation. Mediates transcription activation by binding to the E box (5"-CANNTG-3").
• Source: E.coli
• Species: Human
• Tag: His
• Form: 20mM Tris.Cl, 100mM NaCl, 50% Glycerol, pH8.0.
• Molecular Mass: 27.4kDa(including fusion tag)
• Protein length: 251aa(including fusion tag)
• Applications: WB, ELISA, IP, antibody production, protein array
• Storage: Store at -80°C and avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: ASCL1 achaete-scute complex homolog 1 (Drosophila) [ Homo sapiens ]
• Official Symbol: ASCL1
• Synonyms: ASCL1; ASH1; bHLHa46; HASH1; ASH-1; MASH1
• Gene ID: 429
• mRNA Refseq: NM_004316
• Protein Refseq: NP_004307
• MIM: 100790
• UniProt ID: P50553
• Chromosome Location: Delta-Notch Signaling Pathway, organism-specific biosystem; Notch-mediated HES/HEY network, organism-specific biosystem; SIDS Susceptibility Pathways, organism-specific biosystem
• Pathway: DNA binding; E-box binding; bHLH transcription factor binding; double-stranded DNA binding; protein binding; protein homodimerization activity; sequence-specific DNA binding