Recombinant Human ATIC, fused with N-His tag, was expressed in E. coli.
Bifunctional purine biosynthesis protein PURH is a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity.A mutation in this gene results in AICA-ribosiduria.
20mM Tris.Cl, 50mM NaCl, 50% Glycerol, pH8.0.
66.5kDa(including fusion tag)
607aa(including fusion tag)
WB, ELISA, IP, antibody production, protein array
Store at -80°C and avoid repeated freeze-thaw cycles.