Recombinant Human BIN1 protein, His-tagged

• Cat.No.: BIN1-192H
• Product Overview: Recombinant human BIN1 ( 408 aa, Isoform-10 ) fused with a human Alpha-Fetal Protein N-terminal domain (AFPn)-His-TEV cleavage site at N-terminal was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: 0.2 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, Sucrose and DTT.
• AA Sequence: MTLHRNEYGIASILDSYQCTAEISL ADLATIFFAQFVQEATYKEVSKMVK DALTAIEKPTGDEQSSGCLENQLPA FLEELCHEKEILEKYGHSDCCSQSE EGRHNCFLAHKKPTPASIPLFQVPE PVTSCEAYEEDRETFMNKFIYEIAR RHPFLYAPTILLWAARYDKIIPSCC KAENAVECFQTKAATVTKELRESSG GSHHHHHHGSENLYFQGEFAEMGSK GVTAGKIASNVQKKLTRAQEKVLQK LGKADETKDEQFEQCVQNFNKQLTE GTRLQKDLRTYLASVKAMHEASKKL NECLQEVYEPDWPGRDEANKIAENN DLLWMDYHQKLVDQALLTMDTYLGQ FPDIKSRIAKRGRKLVDYDSARHHY ESLQTAKKKDEAKIAKAEEELIKAQ KVFEEMNVDLQEELPSLWNSRVGFY VNTFQSIAGLEENFHKEMSKLNQNL NDVLVGLEKQHGSNTFTVKAQPSDN APAKGNKSPSPPDGSPAATPEIRVN HEPEPAGGATPGATLPKSPSQSSLP AVVVETFPATVNGTVEGGSGAGRLD LPPGFMFKVQAQHDYTATDTDELQL KAGDVVLVIPFQNPEEQDEGWLMGV KESDWNQHKELEKCRGVFPENFTER VP
• Purity: >90% by SDS-PAGE
• Storage: Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 7 days.

Gene Information

• Gene Name: BIN1 bridging integrator 1 [ Homo sapiens ]
• Official Symbol: BIN1
• Synonyms: BIN1; bridging integrator 1; AMPHL; myc box-dependent-interacting protein 1; AMPH2; amphiphysin II; SH3P9; amphiphysin-like protein; box dependant MYC interacting protein 1; box-dependent myc-interacting protein 1; MGC10367; DKFZp547F068
• Gene ID: 274
• mRNA Refseq: NM_004305
• Protein Refseq: NP_004296
• MIM: 601248
• UniProt ID: O00499
• Chromosome Location: 2q14
• Pathway: Arf6 trafficking events, organism-specific biosystem
• Function: GTPase binding; protein binding; protein heterodimerization activity