Active Recombinant Human BMP4/BMP7 protein
Cat.No. : | BMP4&BMP7-710H |
Product Overview : | Recombinant Human BMP4(Ser293-Arg408)/BMP7(Ser293-His431) was expressed in E. coli. |
- Specification
- Gene Information
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Source : | E. coli |
Species : | Human |
Predicted N Terminal : | Met (BMP-4) & Ser293 (BMP-7) |
Form : | Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA. |
Bio-activity : | Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Nakamura, K. et al. (1999) Exp. Cell Res. 250:351. The ED50 for this effect is typically 15-75 ng/mL. |
Molecular Mass : | Predicted Molecular Mass: 13.3 (BMP-4), 15.8 (BMP-7) kDa |
Protein length : | BMP4(Ser293-Arg408)/BMP7(Ser293-His431) |
Endotoxin : | <0.01 EU per 1 μg of the protein by the LAL method. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | Reconstitute at 100 μg/mL in sterile 4 mM HCl. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Gene Name : | BMP4 bone morphogenetic protein 4 [ Homo sapiens ] |
Official Symbol : | BMP4 |
Synonyms : | BMP4; bone morphogenetic protein 4; BMP2B; BMP-4; BMP-2B; bone morphogenetic protein 2B; ZYME; OFC11; BMP2B1; MCOPS6; |
Gene ID : | 652 |
mRNA Refseq : | NM_001202 |
Protein Refseq : | NP_001193 |
MIM : | 112262 |
UniProt ID : | P12644 |
Chromosome Location : | 14q22-q23 |
Pathway : | Adipogenesis, organism-specific biosystem; Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Glypican 3 network, organism-specific biosystem; Heart Development, organism-specific biosystem; Hedgehog signaling pathway, organism-specific biosystem; Hedgehog signaling pathway, conserved biosystem; |
Function : | BMP receptor binding; chemoattractant activity; cytokine activity; growth factor activity; protein binding; |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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