Recombinant Human BMP4 protein
Cat.No. : | BMP4-261H |
Product Overview : | Recombinant Human BMP4, transcript variant 1, was expressed in HeLa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. |
Source : | HeLa |
Species : | Human |
Form : | Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer, 100mM NaCl, pH 7.2 |
Molecular Mass : | 46.4 |
AA Sequence : | HHSQRARKKNKNCRRHSLYVDFSDV GWNDWIVAPPGYQAFYCHGDCPFPL ADHLNSTNHAIVQTLVNSVNSSIPK ACCVPTELSAISMLYLDEYDKVVLK NYQEMVVEGCGCR |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | Resuspend the protein in the desired concentration in proper buffer |
Gene Name : | BMP4 bone morphogenetic protein 4 [ Homo sapiens ] |
Official Symbol : | BMP4 |
Synonyms : | BMP4; bone morphogenetic protein 4; BMP2B; BMP-4; BMP-2B; bone morphogenetic protein 2B; ZYME; OFC11; BMP2B1; MCOPS6; |
Gene ID : | 652 |
mRNA Refseq : | NM_001202 |
Protein Refseq : | NP_001193 |
MIM : | 112262 |
UniProt ID : | P12644 |
Products Types
◆ Recombinant Protein | ||
Bmp4-324M | Recombinant Mouse Bmp4 Protein, His-tagged | +Inquiry |
Bmp4-323M | Recombinant Mouse Bmp4 Protein, His-tagged | +Inquiry |
BMP4-11H | Active Recombinant Human BMP4 Protein, Pre-aliquoted | +Inquiry |
BMP4-001H | Recombinant Human BMP4 Protein, His-MBP-tagged | +Inquiry |
BMP4-013H | Active Recombinant Human BMP4 Protein | +Inquiry |
◆ Lysates | ||
BMP4-8432HCL | Recombinant Human BMP4 293 Cell Lysate | +Inquiry |
BMP4-8431HCL | Recombinant Human BMP4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionBMP4 can be used in spinal fusion surgery to stimulate bone growth and fuse vertebrae together, which can alleviate back pain and stabilize the spine.
Mutations in BMP4 or its receptors can lead to congenital disorders, such as orofacial clefts and heart defects.
Yes, there are ongoing trials exploring the use of BMP4 in regenerative medicine for conditions like osteoarthritis and tendon injuries.
Yes, some risks include excessive bone growth, swelling, and inflammation at the application site. These complications can be carefully managed by healthcare providers.
Yes, BMP4 can be used to aid in tissue regeneration in cosmetic procedures, such as in the reconstruction of facial bone defects or enhancement of soft tissue volume.
Customer Reviews (3)
Write a reviewThe BMP4 protein is a valuable resource for researchers due to its high quality and its ability to meet specific experimental needs.
the manufacturer's technical support team can offer prompt assistance in case any issues arise during the handling or application of the BMP4 protein.
The manufacturer's support can play a crucial role in assisting researchers throughout their trials.
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