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Active Recombinant Human BMPR1B Protein, His & GST-tagged

Cat.No. : BMPR1B-223H
Product Overview : Recombinant human ALK6 (NP_001194.1) cytoplasmic domain (Arg 149-Leu 502) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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  • Gene Information
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Source : Baculovirus-Insect Cells
Species : Human
Tag : His & GST
Predicted N Terminal : Met
Form : Supplied as sterile 50mM Tris, 100mM NaCl, pH 8.5, 20% gly, 0.3mM DTT.
Bio-activity : Kinase activity untested
Molecular Mass : The recombinant human ALK6 (149-502)/GST chimera consists of 591 amino acids and has a calculated molecular mass of 68.3 KDa. It migrates as an approximately 55 KDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >90 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Gene Name : BMPR1B bone morphogenetic protein receptor type IB [ Homo sapiens ]
Official Symbol : BMPR1B
Synonyms : ALK6; AMDD; ALK-6; CDw293; BMP type-1B receptor; BMPR-1B; activin receptor-like kinase 6; bone morphogenetic protein receptor, type IB; serine/threonine receptor kinase
Gene ID : 658
mRNA Refseq : NM_001203
Protein Refseq : NP_001194
MIM : 603248
UniProt ID : O00238
Chromosome Location : 4q22-q24
Pathway : BMP signaling, organism-specific biosystem; BMP signaling, conserved biosystem; Cytokine-cytokine receptor interaction, conserved biosystem

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can BMPR1B be targeted for regenerative medicine purposes? 02/19/2023

Yes, the role of BMPR1B in tissue regeneration, especially in bone and cartilage, makes it a potential target for regenerative medicine approaches.

In what ways can BMPR1B be targeted for therapeutic purposes? 07/13/2017

Therapeutic strategies may involve the use of small molecules, antibodies, or gene therapies to modulate BMPR1B activity for treating various clinical conditions.

How does BMPR1B protein contribute to fertility in humans? 11/06/2016

BMPR1B is involved in the regulation of ovarian function and follicular development, making it relevant to fertility treatments and reproductive medicine.

How does BMPR1B contribute to the development of the nervous system? 07/25/2016

BMPR1B is involved in neural development, and understanding its role could have implications for neuroregenerative medicine and the treatment of neurodevelopmental disorders.

Is BMPR1B associated with any autoimmune diseases? 02/04/2016

While the direct association with autoimmune diseases is not well-established, the role of BMPR1B in immune regulation might be explored for potential implications in autoimmune disorders.

Customer Reviews (3)

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Reviews
07/24/2021

    Great performance in ELISA.

    02/02/2018

      Researchers can confidently rely on this high-quality protein to produce accurate and reproducible results, thereby accelerating their research progress

      08/15/2017

        Its well-established reputation and reliability further contribute to its suitability for a wide range of experimental designs.

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