Active Recombinant Human BMPR1B Protein, His & GST-tagged
Cat.No. : | BMPR1B-223H |
Product Overview : | Recombinant human ALK6 (NP_001194.1) cytoplasmic domain (Arg 149-Leu 502) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. |
- Specification
- Gene Information
- Related Products
Source : | Baculovirus-Insect Cells |
Species : | Human |
Tag : | His & GST |
Predicted N Terminal : | Met |
Form : | Supplied as sterile 50mM Tris, 100mM NaCl, pH 8.5, 20% gly, 0.3mM DTT. |
Bio-activity : | Kinase activity untested |
Molecular Mass : | The recombinant human ALK6 (149-502)/GST chimera consists of 591 amino acids and has a calculated molecular mass of 68.3 KDa. It migrates as an approximately 55 KDa band in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >90 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | BMPR1B bone morphogenetic protein receptor type IB [ Homo sapiens ] |
Official Symbol : | BMPR1B |
Synonyms : | ALK6; AMDD; ALK-6; CDw293; BMP type-1B receptor; BMPR-1B; activin receptor-like kinase 6; bone morphogenetic protein receptor, type IB; serine/threonine receptor kinase |
Gene ID : | 658 |
mRNA Refseq : | NM_001203 |
Protein Refseq : | NP_001194 |
MIM : | 603248 |
UniProt ID : | O00238 |
Chromosome Location : | 4q22-q24 |
Pathway : | BMP signaling, organism-specific biosystem; BMP signaling, conserved biosystem; Cytokine-cytokine receptor interaction, conserved biosystem |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, the role of BMPR1B in tissue regeneration, especially in bone and cartilage, makes it a potential target for regenerative medicine approaches.
Therapeutic strategies may involve the use of small molecules, antibodies, or gene therapies to modulate BMPR1B activity for treating various clinical conditions.
BMPR1B is involved in the regulation of ovarian function and follicular development, making it relevant to fertility treatments and reproductive medicine.
BMPR1B is involved in neural development, and understanding its role could have implications for neuroregenerative medicine and the treatment of neurodevelopmental disorders.
While the direct association with autoimmune diseases is not well-established, the role of BMPR1B in immune regulation might be explored for potential implications in autoimmune disorders.
Customer Reviews (3)
Write a reviewGreat performance in ELISA.
Researchers can confidently rely on this high-quality protein to produce accurate and reproducible results, thereby accelerating their research progress
Its well-established reputation and reliability further contribute to its suitability for a wide range of experimental designs.
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