Recombinant Human BTK protein, Flag-tagged, Biotinylated

• Cat.No.: BTK-38H
• Product Overview: Recombinant Human BTK [2-659(end) amino acids of accession number NP_000052.1] fused with DYKDDDDK tag at N-terminal was expressed in insect cell and biotinylated.

Specification

• Source: Insect cell
• Species: Human
• Tag: Flag
• Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
• Molecular Mass: 80 kDa
• Purity: >95% as determined by SDS-PAGE and CBB staining
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: BTK Bruton agammaglobulinemia tyrosine kinase [ Homo sapiens ]
• Official Symbol: BTK
• Synonyms: BTK; ATK; PSCTK1; XLA; AT; BPK; IMD1; AGMX1
• Gene ID: 695
• mRNA Refseq: NM_000061
• Protein Refseq: NP_000052
• MIM: 300300
• UniProt ID: Q06187
• Chromosome Location: Xq21.33-q22
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen Activates B Cell Receptor Leading to Generation of Second Messengers, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; BCR signaling pathway, organism-specific biosystem; Class I PI3K signaling events, organism-specific biosystem
• Function: ATP binding; ATP binding; identical protein binding; kinase activity; lipid binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; phosphatidylinositol-3,4,5-trisphosphate binding; protein binding; protein kinase activity; protein tyrosine kinase activity; protein tyrosine kinase activity