Recombinant human C4 gamma domain cDNA ( 1454 – 1744 aa ) fused with T7-His-TEV cleavage site Tag at N-terminal was expressed in E. coli.
1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, Sucrose and DTT.
MASMTGGQQMGRGHHHHHHGNLYFQGGEFEAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRA DLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPS KSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKITQ VLHFTKDVKAAANQMRNFLVRASCRLRLEPGKEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQR AACAQLNDFLQEYGTQGCQV
1. May be used for in vitro human complement C4d mediated cancer cell resistant to complement-mediated damage pathway regulation study by using this protein as coating matrix protein or soluble factor.2. May be used for protein-protein interaction assay.3. Potential Diagnostic biomarker protein for tumors, such as lung cancer.4. As antigen for specific antibody production.
Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 7 days.