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Recombinant Human C4A protein, T7/His-tagged

Cat.No. : C4A-188H
Product Overview : Recombinant human C4 gamma domain cDNA ( 1454 – 1744 aa ) fused with T7-His-TEV cleavage site Tag at N-terminal was expressed in E. coli.
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Source : E. coli
Species : Human
Tag : T7/His
Form : 1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, Sucrose and DTT.
AA Sequence : MASMTGGQQMGRGHHHHHHGNLYFQ GGEFEAPKVVEEQESRVHYTVCIWR NGKVGLSGMAIADVTLLSGFHALRA DLEKLTSLSDRYVSHFETEGPHVLL YFDSVPTSRECVGFEAVQEVPVGLV QPASATLYDYYNPERRCSVFYGAPS KSRLLATLCSAEVCQCAEGKCPRQR RALERGLQDEDGYRMKFACYYPRVE YGFQVKVLREDSRAAFRLFETKITQ VLHFTKDVKAAANQMRNFLVRASCR LRLEPGKEYLIMGLDGATYDLEGHP QYLLDSNSWIEEMPSERLCRSTRQR AACAQLNDFLQEYGTQGCQV
Purity : >90% by SDS-PAGE
Applications : 1. May be used for in vitro human complement C4d mediated cancer cell resistant to complement-mediated damage pathway regulation study by using this protein as coating matrix protein or soluble factor.2. May be used for protein-protein interaction assay.3. Potential Diagnostic biomarker protein for tumors, such as lung cancer.4. As antigen for specific antibody production.
Storage : Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 7 days.
Gene Name : C4A complement component 4A (Rodgers blood group) [ Homo sapiens ]
Official Symbol : C4A
Synonyms : C4A; complement component 4A (Rodgers blood group); complement component 4A; complement C4-A; C4; C4A2; C4A3; C4A4; C4A6; C4B; C4S; CO4; CPAMD2; RG; acidic C4; C4A anaphylatoxin; Rodgers form of C4; acidic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C4AD; MGC164979;
Gene ID : 720
mRNA Refseq : NM_001252204
Protein Refseq : NP_001239133
MIM : 120810
UniProt ID : P0C0L4
Chromosome Location : 6p21.3
Pathway : Activation of C3 and C5, organism-specific biosystem; Complement Activation, Classical Pathway, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Complement cascade, organism-specific biosystem; Immune System, organism-specific biosystem; Initial triggering of complement, organism-specific biosystem;
Function : endopeptidase inhibitor activity;

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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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