Recombinant Human CBX1(1-185 aa) fused with GST tag at N-terminal was expressed in E. coli.
HP1β is a component of constitutive (transcriptionally silent) heterochromatin, recruited through the interaction of the Chromodomain with histone H3 methylated at lysing 9 (H3K9me).
In 50 mM Tris-HCl pH 7.0, 300 mM NaCl, 1 mM DTT, 10% glycerol.
HP1β Chromodomain, Recombinant Human is useful for protein binding and screening experiments examining methylated protein and peptide substrates.
Stable for six months at -80 centigrade from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.