Recombinant human CD300c cDNA (21 – 183 aa, derived from BC022279) fused with T7-His-TEV cleavage site Tag (29aa) at N-terminal was expressed in E. coli.
0.4 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol.
MASMTGGQQMGRGHHHHHHENLYFQGGEFGYFPLSHPMTVAGPVGGSLSVQCRYEKEHRTLNKFWCRPPQILRCD KIVETKGSAGKRNGRVSIRDSPANLSFTVTLENLTEEDAGTYWCGVDTPWLRDFHDPIVEVEVSVFPAGTTTASS PQSSMGTSGPPTKLPVHTWPSVTRKDSPEPSPHPGSLFSNVR
1. May be used for in vitro non-glycosylated CD300c protein mediated TH1 and TH17 cell function regulation with this protein as either coating matrix protein or soluble factor.2. May be used for CD300c protein-protein interaction assay.3. As enzymatic substrate for various proteases.4. As potential biomarker protein for differentiating patients with ulcerative colitis in Crohn"s disease from non-inflammatory diarrhea.5. As antigen for specific antibody production.
Keep at -80centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days.