Recombinant Human CDC42(Q61L) protein, His-tagged
Cat.No. : | CDC42-2637H |
Product Overview : | Recombinant Human CDC42 fused with a histidine tag in the amino-terminus was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The constitutively active form of human Cdc42 protein contains a glutamine to leucine substitution at residue 61. The common name for this mutant is Cdc42(Q61L) or L61Cdc42. The leucine substitution prevents endogenous and GAP-stimulated GTPase activity of Cdc42, hence the protein is always in the active, GTP-bound, state. A similar mutation in Ras (Ras(Q61L)) behaves as an oncogenic mutation. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 2 mM Tris pH 7.6, 0.5 mM MgCl2, 0.5% sucrose and 0.1% dextran. |
Molecular Mass : | ~25 kDa |
Purity : | >70% pure |
Applications : | Cdc42 effector and GAP identification and binding studies; Activation of Cdc42 effectors in vitro and in vivo; Stimulation of Cdc42 phenotype by microinjection into cells |
Gene Name : | CDC42 cell division cycle 42 (GTP binding protein, 25kDa) [ Homo sapiens ] |
Official Symbol : | CDC42 |
Synonyms : | CDC42; cell division cycle 42 (GTP binding protein, 25kDa); cell division cycle 42 (GTP binding protein, 25kD); cell division control protein 42 homolog; CDC42Hs; G25K; G25K GTP-binding protein; GTP-binding protein, 25kD; growth-regulating protein; small GTP binding protein CDC42; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); |
Gene ID : | 998 |
mRNA Refseq : | NM_001039802 |
Protein Refseq : | NP_001034891 |
MIM : | 116952 |
UniProt ID : | P60953 |
Chromosome Location : | 1p36.1 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Axon guidance, organism-specific biosystem; |
Function : | GTP binding; GTP-dependent protein binding; GTPase activity; GTPase activity; mitogen-activated protein kinase kinase kinase binding; nucleotide binding; protein binding; thioesterase binding; |
Products Types
◆ Recombinant Protein | ||
CDC42-0934H | Recombinant Human CDC42 Protein, GST-Tagged | +Inquiry |
CDC42-1484M | Recombinant Mouse CDC42 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC42-1806H | Recombinant Human CDC42 protein(Met1-Cys188), GST-tagged | +Inquiry |
CDC42-143C | Recombinant Cynomolgus Monkey CDC42 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDC42-0936H | Recombinant Human CDC42 Protein, GST-pstS1-Tagged | +Inquiry |
◆ Lysates | ||
CDC42-7655HCL | Recombinant Human CDC42 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0190 | Cdc42 G-LISA Activation Assay Kit (Colorimetric) | +Inquiry |
Kit-0191 | Cdc42 G-LISA Activation Assay Kit (Colorimetric) II | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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