Recombinant Human CDH1 Protein, His-tagged
Cat.No. : | CDH1-198H |
Product Overview : | Recombinant human CDH1 (NP_004351.1) (Met1-Ala709) was expressed with a polyhistidine tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Source : | Baculovirus-Insect Cells |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Gln 23 |
Form : | Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4, 5%~8% trehalose and mannitol. |
Molecular Mass : | The recombinant human CDH1 consists 698 amino acids and predicts a molecular mass of 77.2 kDa. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >90 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | CDH1 cadherin 1, type 1, E-cadherin (epithelial) [ Homo sapiens ] |
Official Symbol : | CDH1 |
Synonyms : | CDH1; cadherin 1, type 1, E-cadherin (epithelial); UVO; cadherin-1; CD324; E Cadherin; uvomorulin; CAM 120/80; E-Cadherin; cell-CAM 120/80; epithelial cadherin; cadherin 1, E-cadherin (epithelial); calcium-dependent adhesion protein, epithelial; CDHE; ECAD; LCAM; Arc-1; |
Gene ID : | 999 |
mRNA Refseq : | NM_004360 |
Protein Refseq : | NP_004351 |
MIM : | 192090 |
UniProt ID : | P12830 |
Chromosome Location : | 16q22.1 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Adherens junctions interactions, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cell adhesionproteins, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; |
Products Types
◆ Recombinant Protein | ||
CDH1-208H | Recombinant Human CDH1 Protein, Fc-tagged | +Inquiry |
Cdh1-10529M | Recombinant Mouse Cdh1 Protein, His (Fc)-Avi-tagged | +Inquiry |
CDH1-3118H | Recombinant Human CDH1 Protein, MYC/DDK-tagged | +Inquiry |
CDH1-0969H | Recombinant Human CDH1 Protein, GST-Tagged | +Inquiry |
CDH1-207H | Recombinant Human CDH1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
CDH1-1892MCL | Recombinant Mouse CDH1 cell lysate | +Inquiry |
CDH1-736RCL | Recombinant Rat CDH1 cell lysate | +Inquiry |
CDH1-938HCL | Recombinant Human CDH1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionCDH1 gene mutations are usually passed on in an autosomal dominant manner, depending on the type and location of the mutation.
Carriers of CDH1 gene mutations should have gastroscopy, ultrasonography, and other related tests to monitor the development and progression of stomach cancer.
For people with mutations in the CDH1 gene, prophylactic total gastrectomy may reduce the risk of diffuse stomach cancer. There is currently no specific treatment to target CDH1 gene mutations.
CDH1 gene mutation is closely related to the occurrence of diffuse gastric cancer, which is a special subtype of gastric cancer with a high degree of invasion and malignancy.
The CDH1 gene encodes a protein called E-calcin that plays an important role in cell adhesion and tissue differentiation. Mutations in the CDH1 gene may affect these processes, resulting in abnormal cell adhesion and tissue differentiation.
CDH1 gene mutations may be associated with the development of a small number of breast cancers, because CDH1 also plays a role in regulating cell adhesion and tissue structure in breast tissue.
Customer Reviews (3)
Write a reviewThis recombinant protein has a very short half-life and shows a very high clearance rate, which makes its biological activity more stable.
The protein was highly purified and was not doped with other proteins or impurities.
CDH1 has similar activity to the native protein and is able to perform the expected biological functions.
Ask a Question for All CDH1 Products
Required fields are marked with *
My Review for All CDH1 Products
Required fields are marked with *
Inquiry Basket