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Recombinant Human CDNF protein

Cat.No. : CDNF-256H
Product Overview : Recombinant Human CDNF was expressed in CHO.
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  • Gene Information
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Description : CDNF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- (Lindholm et al. 20007; Voutilainen et al., 2011) and MPTP-induced degeneration (Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson’s disease. When administered after 6-OHDA or MPTP –lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.
Source : CHO
Species : Human
Form : PBS pH 7.4
Molecular Mass : Approximately 18.5 kDa, a single non-glycosylated polypeptide chain containing 163 amino acids.
Protein length : 163 amino acids
Endotoxin : Less than 1EU/mg of protein as determined by LAL method.
Storage : Store at -70 centigrade upon receipt. Recommended to aliquot into smaller quantities. Avoid repeated freeze-thaw cycles
Concentration : 1 mg/ml Concentration of the protein is determined by BCA Protein Analysis kit (Pierce). BSA was used as a standard.
Gene Name : CDNF cerebral dopamine neurotrophic factor [ Homo sapiens ]
Official Symbol : CDNF
Synonyms : CDNF; cerebral dopamine neurotrophic factor; arginine rich, mutated in early stage tumors like 1 , ARMETL1; conserved dopamine neurotrophic factor; ARMET-like protein 1; arginine-rich, mutated in early stage tumors-like 1; ARMETL1;
Gene ID : 441549
mRNA Refseq : NM_001029954
Protein Refseq : NP_001025125
MIM : 611233
UniProt ID : Q49AH0
Chromosome Location : 10p13
Function : growth factor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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