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Recombinant Human CGB3 protein, His-tagged

Cat.No. : CGB3-130H
Product Overview : Recombinant Human CGB3(21-165aa) fused with His tag at C-terminal was expressed in Insect cells.
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Description : CGB3, also known as choriogonadotropin subunit beta, is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). It stimulates the expression of GCM1 target genes, including the fusogenic protein syncytin-1, to promote placental cell fusion. It synthesized in large quantities by the developing placenta, reaching peak concentrations in maternal blood during the late first trimester and early midtrimester of pregnancy. It is expressed exclusively by trophoblasts. It is an important biomarker in pregnancy and oncology, where it is routinely detected and quantified by specific immunoassays.
Source : Insect cells
Species : Human
Tag : His
Form : Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Molecular Mass : 16.6kDa (154aa)
18-28kDa (SDS-PAGE under reducing conditions)
AA Sequence : ADPSKEPLRP RCRPINATLA VEKEGCPVCI TVNTTICAGY CPTMTRVLQG VLPALPQVVC NYRDVRFESI RLPGCPRGVN PVVSYAVALS
CQCALCRRST TDCGGPKDHP LTCDDPRFQD SSSSKAPPPS LPSPSRLPGP SDTPILPQHH HHHH
Endotoxin : < 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity : > 90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.25mg/ml (determined by Absorbance at 280nm)
Gene Name : CGB3 chorionic gonadotropin beta subunit 3 [ Homo sapiens ]
Official Symbol : CGB3
Synonyms : CGB; CGB5; CGB7; CGB8; hCGB; CG-beta; chorionic gonadotrophin chain beta; chorionic gonadotropin beta 3 subunit; chorionic gonadotropin beta chain; chorionic gonadotropin chain beta; chorionic gonadotropin, beta polypeptide
Gene ID : 1082
mRNA Refseq : NM_000737
Protein Refseq : NP_000728
MIM : 118860
UniProt ID : P0DN86
Chromosome Location : 19q13.33
Pathway : Gene Expression, organism-specific biosystem; Glycoprotein hormones, organism-specific biosystem; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors, organism-specific biosystem

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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