Recombinant Human CLEC10A protein, His-tagged
Cat.No. : | CLEC10A-308H |
Product Overview : | Recombinant Human CLEC10A(Gln61-His316) fused with His tag at the N-terminus was expressed in NS0. |
- Specification
- Gene Information
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Source : | Mammalian cells |
Species : | Human |
Tag : | His |
Predicted N Terminal : | His |
Form : | Lyophilized from a 0.2 μm filtered solution in PBS. |
Molecular Mass : | Predicted Molecular Mass: 29.6 kDa;SDS-PAGE: 40-43 kDa, reducing conditions. |
Protein length : | Gln61-His316 |
Endotoxin : | <0.01 EU per 1 μg of the protein by the LAL method. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 centigrade as supplied.1 month, 2 to 8 centigrade under sterile conditions after reconstitution.3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | Reconstitute at 200 μg/mL in sterile PBS. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Gene Name : | CLEC10A C-type lectin domain family 10, member A [ Homo sapiens ] |
Official Symbol : | CLEC10A |
Synonyms : | CLEC10A; C-type lectin domain family 10, member A; C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 14 (macrophage derived) , CLECSF13, CLECSF14; C-type lectin domain family 10 member A; CD301; HML; HML2; macrophage lectin 2 (calcium dependent); C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13 (macrophage-derived); C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 14 (macrophage-derived); MGL; CLECSF13; CLECSF14; |
Gene ID : | 10462 |
mRNA Refseq : | NM_006344 |
Protein Refseq : | NP_006335 |
MIM : | 605999 |
UniProt ID : | Q8IUN9 |
Chromosome Location : | 17p13.2 |
Function : | binding; sugar binding; |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionResearchers are exploring the potential of targeting CLEC10A to modulate immune responses against cancer and infectious diseases, with the aim of developing novel immunotherapies.
CLEC10A functions as a receptor on immune cells, where it can recognize specific glycan structures on pathogens and tumor cells, leading to immune cell activation and modulation of immune responses.
Modulating CLEC10A activity could have therapeutic implications for cancer immunotherapy, infectious disease treatment, and potentially other immune-related disorders.
CLEC10A expression on tumor-associated macrophages and dendritic cells can influence the immune response within the tumor microenvironment, potentially impacting tumor growth and metastasis.
CLEC10A is primarily expressed on dendritic cells and macrophages in the immune system, where it plays a role in antigen presentation and immune regulation.
Customer Reviews (3)
Write a reviewThe CLEC10A protein exhibits remarkable performance in Western blotting (WB) experiments.
The versatility and efficacy of CLEC10A in these applications make it an invaluable tool for researchers.
Researchers can rely on CLEC10A to deliver reliable and accurate results in ELISA experiments, ensuring precise measurement and quantification of target proteins.
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