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Recombinant Human CLEC4E protein, His-tagged

Cat.No. : CLEC4E-15H
Product Overview : Recombinant human CLEC4E, fused to His-tag at N-terminus, was expressed in E.coli.
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  • Gene Information
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Description : CLEC4E also known as C-type lectin domain family 4, member E. CLEC4E is a C-type lectin receptor expressed by a variety of antigen presenting cells including macrophages, neutrophils, dendritic cells and B cells; a variety of stimuli including stress are known to induce the expression of CLEC4E.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris 8.0 containing 10% glycerol
Molecular Mass : 22.9kDa (200aa)
AA Sequence : MGSSHHHHHH SSGLVPRGSH MRCVVTFRIF QTCDEKKFQL PENFTELSCY NYGSGSVKNC CPLNWEYFQS SCYFFSTDTI SWALSLKNCSAMGAHLVVIN SQEEQEFLSY KKPKMREFFI GLSDQVVEGQ WQWVDGTPLT KSLSFWDVGE PNNIATLEDC ATMRDSSNPR QNWNDVTCFLNYFRICEMVG INPLNKGKSL
Purity : > 85% by SDS - PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.25mg/ml (determined by Bradford assay)
Gene Name : CLEC4E C-type lectin domain family 4, member E [ Homo sapiens ]
Official Symbol : CLEC4E
Synonyms : CLEC4E; C-type lectin domain family 4, member E; C type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 9 , CLECSF9; C-type lectin domain family 4 member E; mincle; C-type lectin superfamily member 9; macrophage-inducible C-type lectin; C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 9; MINCLE; CLECSF9;
Gene ID : 26253
mRNA Refseq : NM_014358
Protein Refseq : NP_055173
MIM : 609962
UniProt ID : Q9ULY5
Chromosome Location : 12p13.31
Pathway : Tuberculosis, organism-specific biosystem; Tuberculosis, conserved biosystem;
Function : binding; receptor activity; sugar binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can CLEC4E protein be targeted for the treatment of autoimmune diseases? 04/01/2022

While the role of CLEC4E in autoimmune diseases is still being investigated, targeting CLEC4E may hold potential for modulating immune responses in certain autoimmune conditions.

How does CLEC4E protein contribute to immune responses? 07/23/2021

CLEC4E protein activates immune cells and initiates inflammatory responses upon recognition of pathogen-associated molecular patterns (PAMPs).

Is CLEC4E protein involved in antiviral immune responses? 01/26/2021

Yes, CLEC4E is involved in recognizing viral pathogens and triggering immune responses to combat viral infections.

How does CLEC4E protein interact with other immune receptors? 07/12/2019

CLEC4E can collaborate with other immune receptors, such as TLRs (Toll-like receptors), to amplify immune responses upon pathogen detection.

Are there any specific diseases where targeting CLEC4E shows promise? 10/15/2017

Targeting CLEC4E holds promise in the development of vaccines and immunotherapies against infectious diseases, including tuberculosis and fungal infections.

Customer Reviews (3)

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Reviews
10/24/2022

    The CLEC4E protein is an exceptional protein solution that exceeds expectations in terms of quality and suitability for my experimental requirements.

    01/01/2021

      I am confident that utilizing the CLEC4E protein will empower me to uncover crucial insights into cellular mechanisms with precision.

      03/11/2020

        In addition to its outstanding quality, the CLEC4E protein comes with exceptional technical support from its manufacturer.

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