Recombinant Human COPS2 protein, T7/His-tagged

• Cat.No.: COPS2-24H
• Product Overview: Recombinant Human COPS2 fused with with a small T7-His Tag (29aa) fusion at N-terminal was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: T7/His
• Form: Sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, Sucrose and DTT.
• AA Sequence: MASMTGGQQMGRGHHHHHHENLYFQ GGEFSDMEDDFMCDDEEDYDLEYSE DSNSEPNVDLENQYYNSKALKEDDP KAALSSFQKVLELEGEKGEWGFKAL KQMIKINFKLTNFPEMMNRYKQLLT YIRSAVTRNYSEKSINSILDYISTS KQMDLLQEFYETTLEALKDAKNDRL WFKTNTKLGKLYLEREEYGKLQKIL RQLHQSCQTDDGEDDLKKGTQLLEI YALEIQMYTAQKNNKKLKALYEQSL HIKSAIPHPLIMGVIRECGGKMHLR EGEFEKAHTDFFEAFKNYDESGSPR RTTCLKYLVLANMLMKSGINPFDSQ EAKPYKNDPEILAMTNLVSAYQNND ITEFEKILKTNHSNIMDDPFIREHI EELLRNIRTQVLIKLIKPYTRIHIP FISKELNIDVADVESLLVQCILDNT IHGRIDQVNQLLELDHQKRGGARYT ALDKWTNQLNSLNQAVVSKLA
• Purity: > 90% by SDS-PAGE.
• Applications: 1. May be used for in vitro COPS2 mediated ubiquitin pathway regulation study in COP9 signalosome complex for early stage of neuronal differentiation by intracellular delivery of this protein with ProFectin Reagent.
  2. May be used for protein-protein interaction mapping.
  3. May be used as specific substrate protein for kinase, ad ubiquitin (Sumo pathway) related enzyme functional screening assays.
  4. Potential early diagnostic biomarker protein for gastric cancer.
  5. As immunogen for specific antibody production.
• Storage: In Liquid. Keep at -80 centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: COPS2 COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) [ Homo sapiens ]
• Official Symbol: COPS2
• Synonyms: COPS2; COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis); COP9 signalosome complex subunit 2; ALIEN; CSN2; TRIP15; TRIP-15; alien homolog; signalosome subunit 2; TR-interacting protein 15; JAB1-containing signalosome subunit 2; thyroid receptor interacting protein 15; thyroid receptor-interacting protein 15; SGN2
• Gene ID: 9318
• mRNA Refseq: NM_004236
• Protein Refseq: NP_004227
• MIM: 604508
• UniProt ID: P61201
• Chromosome Location: 15q21.2
• Function: protein binding; signal transducer activity