Active Recombinant Human CSTA protein, His-tagged
Cat.No. : | CSTA-203H |
Product Overview : | Recombinant human CSTA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | CSTA, also known as Stefin A, is thiol protease inhibitors that form complexes with papain and the cathepsins B, H and L. The protein is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. CSTA is thought to be a tumor suppressor, since an inverse correlation seems to exist between the level of CSTA and tumor progression, in several malignancies |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol |
Bio-activity : | The IC50 value is < 1.0nM. The inhibitory function of Cystatin A on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C. |
Molecular Mass : | 13.1 kDa (118aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MIPGGLSEAK PATPEIQEIV DKVKPQLEEK TNETYGKLEA VQYKTQVVAG TNYYIKVRAG DNKYMHLKVFKSLPGQNEDL VLTGYQVDKN KDDELTGF |
Purity : | > 95% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by BCA assay) |
Gene Name : | CSTA cystatin A (stefin A) [ Homo sapiens ] |
Official Symbol : | CSTA |
Synonyms : | CSTA; cystatin A (stefin A); STF1; STFA; CSTA; Cystatin-A; Cystatin-AS; cystatin A; cystatin AS; stefin A |
Gene ID : | 1475 |
mRNA Refseq : | NM_005213 |
Protein Refseq : | NP_005204 |
MIM : | 184600 |
UniProt ID : | P01040 |
Chromosome Location : | 3q21 |
Function : | cysteine-type endopeptidase inhibitor activity; protease binding; protein binding, bridging; structural molecule activity |
Products Types
◆ Recombinant Protein | ||
CSTA-894R | Recombinant Rhesus Macaque CSTA Protein, His (Fc)-Avi-tagged | +Inquiry |
CSTA-2014H | Recombinant Human CSTA Protein, His-tagged | +Inquiry |
CSTA-2037H | Recombinant Human CSTA Protein, GST-tagged | +Inquiry |
CSTA-861P | Recombinant Pig CSTA Protein, His-tagged | +Inquiry |
CSTA-226H | Recombinant Human CSTA protein(Ile2-Phe98), His-tagged | +Inquiry |
◆ Lysates | ||
CSTA-7225HCL | Recombinant Human CSTA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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