Recombinant Human CTSD protein, His-tagged

• Cat.No.: CTSD-522H

Specification

• Product overview: Recombinant Human CTSD (P07339) fused with His tag was produced in HEK293F cells.
• Description: This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
• Source: HEK293F
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: CTSD cathepsin D [ Homo sapiens (human) ]
• Official Symbol: CTSD
• Synonyms: CTSD; CPSD; CLN10; HEL-S-130P; cathepsin D; ceroid-lipofuscinosis, neuronal 10; epididymis secretory sperm binding protein Li 130P; lysosomal aspartyl peptidase; lysosomal aspartyl protease
• Gene ID: 1509
• mRNA Refseq: NM_001909.4
• Protein Refseq: NP_001900.1
• UniProt ID: P07339