Recombinant Human DLG4 protein, His-tagged

• Cat.No.: DLG4-18H
• Product Overview: Recombinant Human Disks large homolog 4/DLG4/PSD95 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Leu724) of Human DLG4 fused with a polyhistidine tag at the N-terminus.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4
• AA Sequence: MNHKVHHHHHHMDCLCIVTTKKYRY QDEDTPPLEHSPAHLPNQANSPPVI VNTDTLEAPGYELQV NGTEGEMEYEEITLERGNSGLGFSI AGGTDNPHIGDDPSIFITKIIPGGA AAQDGRLRVNDSILF VNEVDVREVTHSAAVEALKEAGSIV RLYVMRRKPPAEKVMEIKLIKGPKG LGFSIAGGVGNQHIP GDNSIYVTKIIEGGAAHKDGRLQIG DKILAVNSVGLEDVMHEDAVAALKN TYDVVYLKVAKPSNA YLSDSYAPPDITTSYSQHLDNEISH SSYLGTDYPTAMTPTSPRRYSPVAK DLLGEEDIPREPRRI VIHRGSTGLGFNIVGGEDGEGIFIS FILAGGPADLSGELRKGDQILSVNG VDLRNASHEQAAIAL KNAGQTVTIIAQYKPEEYSRFEAKI HDLREQLMNSSLGSGTASLRSNPKR GFYIRALFDYDKTKD CGFLSQALSFRFGDVLHVIDAGDEE WWQARRVHSDSETDDIGFIPSKRRV ERREWSRLKAKDWGS SSGSQGREDSVLSYETVTQMEVHYA RPIIILGPTKDRANDDLLSEFPDKF GSCVPHTTRPKREYE IDGRDYHFVSSREKMEKDIQAHKFI EAGQYNSHLYGTSVQSVREVAEQGK HCILDVSANAVRRLQ AAHLHPIAIFIRPRSLENVLEINKR ITEEQARKAFDRATKLEQEFTECFS AIVEGDSFEEIYHKV KRVIEDLSGPYIWVPARERL
• Endotoxin: Less than 0.1 ng/µg (1 IEU/µg).
• Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
• Storage: Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days.Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months.
• Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in 1X PBS.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Gene Information

• Gene Name: DLG4 discs, large homolog 4 (Drosophila) [ Homo sapiens ]
• Official Symbol: DLG4
• Synonyms: DLG4; discs, large homolog 4 (Drosophila); disks large homolog 4; PSD 95; PSD95; SAP 90; SAP90; discs large homolog 4; Tax interaction protein 15; synapse-associated protein 90; postsynaptic density protein 95; post-synaptic density protein 95; SAP-90; FLJ97752; FLJ98574
• Gene ID: 1742
• mRNA Refseq: NM_001365
• Protein Refseq: NP_001356
• MIM: 602887
• UniProt ID: P78352
• Chromosome Location: 17p13.1
• Pathway: Activation of Ca-permeable Kainate Receptor, organism-specific biosystem; Activation of Kainate Receptors upon glutamate binding, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Axon guidance, organism-specific biosystem; CREB phosphorylation through the activation of CaMKII, organism-specific biosystem; CREB phosphorylation through the activation of Ras, organism-specific biosystem; Cocaine addiction, organism-specific biosystem
• Function: protein C-terminus binding; protein binding; scaffold protein binding