Recombinant Human DNM2(aa 533-731) fused with His/T7 tag was expressed in E. coli.
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts.
Lyophilized from PBS, pH 7.4, 5% trehalose, 0.01% sarcosyl
Store at +4 centigradefor up to 1 month, or aliquot and store at -80 centigradefor up to 12 months. Avoid repeat freeze-thaw cycles.
Reconstitute in sterile PBS, pH 7.2-7.4.