"DOT1L" Related Products

Expand

Recombinant Human DOT1L protein, GST-tagged

Cat.No.: DOT1L-256H
Product Overview: Recombinant Human DOT1L(1-472 aa)(Catalytic Domain) fused with GST tag at N-terminal was expressed in E. coli.
Description: DOT1 is a histone methyltransferase, catalyzing the methylation of histone H3 at lysine 79 on nucleosomal substrates.
Source: E. coli
Species: Human
Tag : GST
Form: 100 mM Tris pH 8.0, 5 mM glutathione and 25% glycerol.
Molecular Mass: 85 kDa
Applications: Recombinant DOT1L Catalytic Domain, human is useful for histone H3 methylation experiments, enzyme kinetics and inhibitor screening. Use of 3-5 µg DOT1L per reaction with HeLa or recombinant nucleosomes as a substrate is recommended.
Storage: Stable for six months at -80 centigrade from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.
Concentration: 1 µg/µl
Gene Name: DOT1L DOT1-like, histone H3 methyltransferase (S. cerevisiae) [ Homo sapiens ]
Official Symbol: DOT1L
Synonyms: DOT1L; DOT1-like, histone H3 methyltransferase (S. cerevisiae); histone-lysine N-methyltransferase, H3 lysine-79 specific; DOT1; histone methyltransferase DOT1L; KIAA1814; KMT4; H3-K79-HMTase; DOT1-like protein; lysine N-methyltransferase 4; histone H3-K79 methyltransferase; DKFZp586P1823;
Gene ID: 84444
mRNA Refseq: NM_032482
Protein Refseq: NP_115871
MIM: 607375
UniProt ID: Q8TEK3
Chromosome Location: 19p13.3
Pathway: Lysine degradation, organism-specific biosystem; Lysine degradation, conserved biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem;

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.