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Recombinant Human DPY30 protein, His-tagged

Cat.No. : DPY30-315H
Product Overview : Recombinant full-length human DPY30 was expressed in E.coli cells using an N-terminal His tag.
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Description : As a core subunit of the SET1/MLL histone methyl-transferase complexes, DPY30 modulates H3K4 methylation in vitro, and directly regulates chromosomal H3K4 trimethylation (H3K4me3) throughout the mam-malian genome. The methylation event has been shown to affect embryonic stem cells (ESCs) maintenance and differentiation. Depletion of Dpy-30 does not affect ESC self-renewal, but significantly alters the differentiation potential of ESCs, particularly along the neural lineage.
Source : E.coli
Species : Human
Tag : His
Form : 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol
Molecular Mass : 20 kDa
Purity : The purity of DPY30 was determined to be >95% by densitometry.
Applications : Enzyme Assay; WB
Stability : 1 year at -70 centigrade
Storage : Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 μg/μL
Gene Name : histone methyltransferase complex regulatory subunit [ Homo sapiens (human) ]
Official Symbol : DPY30
Synonyms : Cps25; Saf19; HDPY-30
Gene ID : 84661
mRNA Refseq : NM_032574
Protein Refseq : NP_115963
MIM : 612032
UniProt ID : Q9C005

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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