Recombinant Human EP300 Protein, GST-tagged
Cat.No. : | EP300-43H |
Product Overview : | Recombinant human EP300 protein containing an N-terminal GST tag, was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | P300 is potent transcriptional coactivator and binds directly to a number of transcription factors including CREB, HIF1A and TFAP2A. P300 contains histone acetyltransferase activity, as well as a Bromodomain, through which it interacts with acetylated histones. |
Source : | E. coli |
Species : | Human |
Tag : | GST |
Molecular Mass : | 46 kDa |
Notes : | This product is for in vitro research use only and is not intended for use in humans or animals. |
Storage : | Stable for six months at -80 centigrade from date of receipt. For best results, aliquot and avoid multiple freeze/thaws. |
Concentration : | 1 mg/mL |
Storage Buffer : | 20 mM Tris-HCl pH 8.0, 200 mM NaCl, 1 mM DTT, 20% glycerol |
Gene Name : | EP300 E1A binding protein p300 [ Homo sapiens (human) ] |
Official Symbol : | EP300 |
Synonyms : | EP300; E1A binding protein p300; p300; KAT3B; RSTS2; histone acetyltransferase p300; E1A-associated protein p300; E1A-binding protein, 300kD; histone butyryltransferase p300; histone crotonyltransferase p300; p300 HAT; protein propionyltransferase p300; EC 2.3.1.48 |
Gene ID : | 2033 |
mRNA Refseq : | NM_001429 |
Protein Refseq : | NP_001420 |
MIM : | 602700 |
UniProt ID : | Q09472 |
Products Types
◆ Recombinant Protein | ||
EP300-02H | Recombinant Human EP300 Protein, N-Flag-tagged | +Inquiry |
EP300-12H | Recombinant Human EP300 Protein (bromodomain, 1041-1161), N-His and C-Flag-tagged | +Inquiry |
EP300-04H | Recombinant Human EP300 Protein (catalytic domain, 965-1810), N-Flag-tagged | +Inquiry |
Ep300-415M | Recombinant Mouse Ep300 Protein, His-tagged | +Inquiry |
EP300-01D | Recombinant Dog Ep300 Protein, His tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
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Q&As (5)
Ask a questionEP300 is crucial for embryonic development, and mutations in the EP300 gene can lead to developmental abnormalities. Understanding its role is essential for potential interventions.
EP300 is involved in neuronal function and survival. Dysregulation of EP300 has been observed in neurodegenerative diseases like Alzheimer's and Parkinson's.
Research is underway to explore drugs that modulate EP300 activity for potential therapeutic interventions in neurodegenerative disorders, but clinical applications are still in the early stages.
Yes, there are clinical trials exploring the therapeutic potential of targeting EP300 in various cancer types, focusing on its role in controlling cell proliferation and survival.
While there are no specific drugs targeting EP300 approved for cardiovascular diseases, ongoing research aims to identify compounds that can modulate its activity for therapeutic purposes.
Customer Reviews (3)
Write a reviewIt has consistently demonstrated outstanding results, consistently producing clear and sharp bands, allowing for accurate and reliable protein detection and quantification.
Its stability and purity make it an ideal candidate for studying protein structures at a high resolution, providing crucial insights into the organization and function of the EP300 protein.
I highly recommend the EP300 protein for its exceptional performance in Western blot analysis.
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