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Recombinant Human EP300 Protein, GST-tagged

Cat.No. : EP300-43H
Product Overview : Recombinant human EP300 protein containing an N-terminal GST tag, was expressed in E. coli.
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  • Gene Information
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Description : P300 is potent transcriptional coactivator and binds directly to a number of transcription factors including CREB, HIF1A and TFAP2A. P300 contains histone acetyltransferase activity, as well as a Bromodomain, through which it interacts with acetylated histones.
Source : E. coli
Species : Human
Tag : GST
Molecular Mass : 46 kDa
Notes : This product is for in vitro research use only and is not intended for use in humans or animals.
Storage : Stable for six months at -80 centigrade from date of receipt. For best results, aliquot and avoid multiple freeze/thaws.
Concentration : 1 mg/mL
Storage Buffer : 20 mM Tris-HCl pH 8.0, 200 mM NaCl, 1 mM DTT, 20% glycerol
Gene Name : EP300 E1A binding protein p300 [ Homo sapiens (human) ]
Official Symbol : EP300
Synonyms : EP300; E1A binding protein p300; p300; KAT3B; RSTS2; histone acetyltransferase p300; E1A-associated protein p300; E1A-binding protein, 300kD; histone butyryltransferase p300; histone crotonyltransferase p300; p300 HAT; protein propionyltransferase p300; EC 2.3.1.48
Gene ID : 2033
mRNA Refseq : NM_001429
Protein Refseq : NP_001420
MIM : 602700
UniProt ID : Q09472

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does EP300 impact developmental abnormalities? 11/12/2022

EP300 is crucial for embryonic development, and mutations in the EP300 gene can lead to developmental abnormalities. Understanding its role is essential for potential interventions.

How does EP300 contribute to neurodegenerative disorders? 09/22/2021

EP300 is involved in neuronal function and survival. Dysregulation of EP300 has been observed in neurodegenerative diseases like Alzheimer's and Parkinson's.

Are there experimental treatments targeting EP300 in neurodegenerative disorders? 06/20/2021

Research is underway to explore drugs that modulate EP300 activity for potential therapeutic interventions in neurodegenerative disorders, but clinical applications are still in the early stages.

Are there any ongoing clinical trials targeting EP300 in cancer treatment? 07/07/2017

Yes, there are clinical trials exploring the therapeutic potential of targeting EP300 in various cancer types, focusing on its role in controlling cell proliferation and survival.

Are there drugs targeting EP300 in cardiovascular diseases? 03/26/2016

While there are no specific drugs targeting EP300 approved for cardiovascular diseases, ongoing research aims to identify compounds that can modulate its activity for therapeutic purposes.

Customer Reviews (3)

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Reviews
09/22/2022

    It has consistently demonstrated outstanding results, consistently producing clear and sharp bands, allowing for accurate and reliable protein detection and quantification.

    03/09/2021

      Its stability and purity make it an ideal candidate for studying protein structures at a high resolution, providing crucial insights into the organization and function of the EP300 protein.

      07/07/2016

        I highly recommend the EP300 protein for its exceptional performance in Western blot analysis.

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