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Active Recombinant Human EPOR & CD131 Protein, Fc-tagged

Cat.No. : EPOR & CD131-1241H
Product Overview : Recombinant extracellular domain (Met 1-Pro 250) of human EPOR (NP_000112.1) linked with the extracellular domain (Trp 17-Trp 443) of human CD131 (NP_000386.1) by a peptide linker was fused with the Fc region of human IgG1 at the C-terminus.
  • Specification
  • Gene Information
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Source : HEK293
Species : Human
Tag : Fc
Predicted N Terminal : Ala 25
Form : Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
Bio-activity : 1. Measured by its ability to bind rat EPO-His in a functional ELISA. 2. Measured by its ability to bind mouse EPO-His in a functional ELISA.
Molecular Mass : The recombinant human EPOR&CD131/Fc chimera is a disulfide-linked homodimer of EPOR&CD131-Fc heterodimer. The reduced EPOR& CD131-Fc comprises 906 amino acids and has a calculated molecular mass of 101 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 125 kDa in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >90 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : EPOR erythropoietin receptor [ Homo sapiens ]
Official Symbol : EPOR
Synonyms : EPOR; erythropoietin receptor; EPO-R; MGC138358;
Gene ID : 2057
mRNA Refseq : NM_000121
Protein Refseq : NP_000112
MIM : 133171
UniProt ID : P19235
Chromosome Location : 19p13.3-p13.2
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; EPO Receptor Signaling, organism-specific biosystem; EPO signaling pathway, organism-specific biosystem; Hematopoietic cell l
Function : erythropoietin receptor activity; identical protein binding; protein binding; receptor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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