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Active Recombinant Human FGF18 Protein, His-tagged

Cat.No. : FGF18-504H
Product Overview : Recombinant human FGF18 (O76093) (Met 1-Ala 207) was fused with a polyhistidine tag at the C-terminus.
  • Specification
  • Gene Information
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Source : HEK293
Species : Human
Tag : His
Predicted N Terminal : Glu 28
Form : Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.
Bio-activity : 1. Measured by its binding ability in a functional ELISA.2. Immobilized human FGF18 at 10 μg/mL (100 μl/well) can bind Rat FGFR4, The EC50 of Rat FGFR4 is 1.17 μg/mL.
Molecular Mass : The secreted recombinant human FGF18 comprises 191 amino acids and has a predicted molecular mass of 22.3 kDa. The apparent molecular mass of rh FGF18 is approximately 32 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Protein length : Met 1-Ala 207
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >92 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70°C.
Storage : Store it under sterile conditions at -20°C~-70°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : FGF18 fibroblast growth factor 18 [ Homo sapiens ]
Official Symbol : FGF18
Synonyms : FGF18; fibroblast growth factor 18; FGF 18; ZFGF5; FGF-18;
Gene ID : 8817
mRNA Refseq : NM_003862.2
Protein Refseq : NP_003853.1
MIM : 603726
UniProt ID : O76093

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What are the potential side effects of FGF18 therapy? 12/04/2021

While generally considered safe, potential side effects may include local reactions at the injection site. Comprehensive studies are ongoing to assess long-term safety.

Is FGF18 only applicable to bone-related conditions? 05/04/2021

While its primary focus is on musculoskeletal conditions, FGF18's role in cellular growth and repair suggests potential applications in other medical fields.

How does FGF18 compare to other growth factors in terms of clinical applications? 07/03/2020

Comparative studies are underway to evaluate the effectiveness and safety of FGF18 against other growth factors in various clinical scenarios.

Are there any ongoing clinical trials involving FGF18? 12/22/2019

Yes, there are several clinical trials exploring the safety and efficacy of FGF18 in various musculoskeletal disorders and conditions.

How does FGF18 contribute to the treatment of osteoarthritis? 07/08/2017

FGF18 has shown promise in promoting cartilage repair and regeneration, making it a potential candidate for the development of therapies for osteoarthritis.

Customer Reviews (3)

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Reviews
01/09/2022

    the FGF18 protein exhibits remarkable stability, enabling it to maintain its structural integrity and functionality throughout the experimental process.

    05/30/2021

      The FGF18 protein offers exceptional quality and purity, which is crucial for ensuring reliable and reproducible experimental outcomes.

      12/08/2017

        As a researcher utilizing the FGF18 protein, I am fortunate to benefit from its numerous advantages in trials.

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